Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.32 |
| ▸ | MC4R | P32245 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4884870 | 0.92 | — | — | |
| SCHEMBL4018846 | 0.86 | MGLL (0.36) | MGLLMC4RKCNH2 | |
| SCHEMBL4024700 | 0.85 | MGLL (0.35) | MGLLKCNH2 | |
| SCHEMBL4023656 | 0.82 | MGLL (0.38) | MGLL | |
| SCHEMBL4025189 | 0.82 | MGLL (0.38) | MGLLHCRTR1HCRTR2 | |
| SCHEMBL4025192 | 0.82 | MGLL (0.38) | MGLLHCRTR1HCRTR2 | |
| SCHEMBL4023658 | 0.82 | MGLL (0.38) | MGLL | |
| SCHEMBL4021116 | 0.81 | SLC6A2 (0.35) | MGLL | |
| SCHEMBL4749182 | 0.81 | MGLL (0.39) | MGLL | |
| SCHEMBL4751652 | 0.81 | MGLL (0.39) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | claimed |