Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4030746 | 0.93 | KMT2A (0.33) | L3MBTL1OPRL1KMT2AKDM5APDCD1LG2 | |
| SCHEMBL4025390 | 0.86 | OPRM1 (0.37) | OPRL1KDM5APDCD1LG2CD274OPRM1 | |
| SCHEMBL4031855 | 0.80 | KDM5A (0.34) | OPRL1KDM5A | |
| SCHEMBL4023855 | 0.80 | KDM5A (0.34) | OPRL1KDM5A | |
| SCHEMBL4025157 | 0.80 | KDM5A (0.34) | OPRL1KDM5A | |
| SCHEMBL4028519 | 0.79 | PDE5A (0.38) | KMT2AKDM5A | |
| SCHEMBL4024429 | 0.78 | OPRL1 (0.35) | OPRL1KDM5APDCD1LG2CD274 | |
| SCHEMBL4029262 | 0.78 | NPY5R (0.35) | OPRL1KDM5A | |
| SCHEMBL4030735 | 0.78 | NPY5R (0.35) | OPRL1KDM5A | |
| SCHEMBL4024067 | 0.78 | NPY5R (0.35) | OPRL1KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029579-A2 | CYCLOHEXYLPYRAZOLE-LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | ELI LILLY AND COMPANY (US) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007124254-A2 | CYCLOHEXYLPYRAZOLE-LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | ELI LILLY AND COMPANY (US) | 2007-11-01 | — | — | WO | disclosed |