SCHEMBL4026009

SCHEMBL4026009

NC(=O)c1cc(Cl)ccc1-c1cccc(Cl)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 2/20 0.52
IKBKB O14920 3/20 0.51
CHUK O15111 1/20 0.51
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 1/20 0.49
GLA P06280 1/20 0.49
GAA P10253 1/20 0.49
CHRM1 P11229 1/20 0.48
NUDT1 P36639 1/20 0.48
BCAT2 O15382 1/20 0.47
JAK2 O60674 1/20 0.46
SLC9A1 P19634 2/20 0.46
CASP1 P29466 2/20 0.45
RORB Q92753 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
ADRA1D P25100 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
FADS1 O60427 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12505389 0.88 TSHR (0.46) PARP1IKBKBCHUKKDM4EALDH1A1
SCHEMBL3632126 0.88 BCAT2 (0.65) PARP1IKBKBCHUKKDM4ECHRM1
SCHEMBL4030359 0.87 BCAT2 (0.63) IKBKBCHUKKDM4EALDH1A1GLA
SCHEMBL27922044 0.80 PARP1 (0.55) PARP1IKBKBCHUKKDM4EBCAT2
SCHEMBL12505479 0.79 HSD17B10 (0.53) IKBKBCHUKKDM4EALDH1A1GLA
SCHEMBL16146601 0.78 TAAR1 (0.49) IKBKBCHUKKDM4EALDH1A1GLA
Hydrochloric Acid SCHEMBL12505442 0.77 TAAR1 (0.47) IKBKBCHUKKDM4EALDH1A1GLA
SCHEMBL30219241 0.77 ALDH1A1 (0.65) KDM4EALDH1A1GLAGAAJAK2
SCHEMBL1086528 0.77 ALDH1A1 (0.65) KDM4EALDH1A1GLAGAAJAK2
SCHEMBL10631523 0.76 RORB (0.57) CHRM1BCAT2RORB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1252140-B1 PYRROLECARBOXAMIDES AND PYRROLETHIOAMIDES AS FUNGICIDES SYNGENTA PARTICIPATIONS AG (CH) 2009-05-13 EP claimed