Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 6/20 | 0.42 |
| ▸ | HTR2C | P28335 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14041491 | 0.82 | BAZ2B (0.47) | BAZ2BLMNAKDM4EGAASIRT1 | |
| SCHEMBL20602364 | 0.82 | MAPT (0.59) | BAZ2BLMNAKDM4ESIRT1MEN1 | |
| SCHEMBL17026942 | 0.81 | KDM4E (0.49) | BAZ2BKDM4EGAAMEN1ALDH1A1 | |
| SCHEMBL4024352 | 0.80 | HSD17B10 (0.56) | BAZ2BLMNAKDM4EHTR2AHTR2C | |
| SCHEMBL4032318 | 0.79 | AR (0.55) | MEN1MAPTMAPK10KMT2A | |
| SCHEMBL17026844 | 0.79 | KIF11 (0.46) | KDM4EMEN1KMT2A | |
| SCHEMBL31510878 | 0.78 | HTR2A (0.51) | BAZ2BLMNAKDM4EHTR2AHTR2C | |
| SCHEMBL31510880 | 0.78 | HTR2A (0.51) | BAZ2BLMNAKDM4EHTR2AHTR2C | |
| SCHEMBL4026240 | 0.78 | KMT2A (0.58) | LMNAKDM4EGAAMEN1ALDH1A1 | |
| SCHEMBL4026759 | 0.75 | KMT2A (0.61) | LMNAKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103022-A1 | DERIVATIVES OF SUBSTITUTED FUSED RING CYCLOINDOLES AND METHODS OF THEIR USE | ITHERX PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | WO | disclosed |