Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 11/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022878 | 0.91 | DRD4 (0.49) | DRD4KDM2BCCR3DRD2KMT2A | |
| SCHEMBL4023627 | 0.82 | KDM2B (0.39) | DRD4KDM2BCCR3DRD2KMT2A | |
| SCHEMBL4023629 | 0.82 | KDM2B (0.39) | DRD4KDM2BCCR3DRD2KMT2A | |
| SCHEMBL13721312 | 0.82 | KDM2B (0.39) | DRD4KDM2BCCR3DRD2KMT2A | |
| SCHEMBL4022127 | 0.82 | KDM2B (0.39) | DRD4KDM2BCCR3DRD2KMT2A | |
| SCHEMBL4751954 | 0.81 | DRD4 (0.44) | DRD4KDM2BCCR3DRD2KMT2A | |
| SCHEMBL4024586 | 0.81 | DRD4 (0.38) | DRD4KDM2BDRD2KMT2ACYP2C9 | |
| SCHEMBL4025349 | 0.80 | DRD4 (0.43) | DRD4KDM2BCCR3DRD2KMT2A | |
| SCHEMBL4776307 | 0.77 | KDM2B (0.37) | DRD4KDM2BCCR3DRD2KMT2A | |
| SCHEMBL4022053 | 0.76 | MGLL (0.36) | KDM2BKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |