Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4028159 | 0.91 | ALDH1A1 (0.39) | ALDH1A1GAAKMT2AMEN1CYP2C9 | |
| SCHEMBL4021692 | 0.89 | ALDH1A1 (0.38) | ALDH1A1GAAKMT2AMEN1CYP2C9 | |
| SCHEMBL4021786 | 0.88 | ALDH1A1 (0.42) | ALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL4780207 | 0.88 | L3MBTL1 (0.37) | ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL4772352 | 0.88 | L3MBTL1 (0.37) | ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL4022116 | 0.87 | CYP2C9 (0.41) | ALDH1A1GAAKMT2AMEN1CYP2C9 | |
| SCHEMBL4020281 | 0.86 | EED (0.34) | ALDH1A1GAAKMT2AMEN1LMNA | |
| SCHEMBL4022948 | 0.85 | ALDH1A1 (0.39) | ALDH1A1GAAKMT2AMEN1CYP2C9 | |
| SCHEMBL4022953 | 0.85 | ALDH1A1 (0.39) | ALDH1A1GAAKMT2AMEN1CYP2C9 | |
| SCHEMBL4019805 | 0.85 | ALDH1A1 (0.41) | ALDH1A1GAAKMT2AMEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |