Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | NPC1 | O15118 | 2/20 | 0.78 |
| ▸ | RAB9A | P51151 | 2/20 | 0.78 |
| ▸ | BCHE | P06276 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 1/20 | 0.78 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.78 |
| ▸ | MAOB | P27338 | 4/20 | 0.74 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | RELA | Q04206 | 1/20 | 0.67 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.67 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.65 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.63 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357635 | 0.89 | ALOX5 (0.78) | LMNANPC1RAB9ABCHEMAPT | |
| SCHEMBL31676388 | 0.89 | ALOX5 (0.78) | LMNANPC1RAB9AALOX5MAOB | |
| SCHEMBL6357636 | 0.89 | ALOX5 (0.78) | LMNANPC1RAB9ABCHEMAPT | |
| SCHEMBL1764954 | 0.88 | ABCG2 (0.86) | LMNANPC1RAB9ABCHEMAPT | |
| SCHEMBL28796418 | 0.88 | ABCG2 (0.86) | LMNANPC1RAB9ABCHEMAPT | |
| SCHEMBL1723179 | 0.88 | MAPT (1.00) | LMNANPC1RAB9ABCHEMAPT | |
| SCHEMBL1723180 | 0.88 | MAPT (1.00) | LMNANPC1RAB9ABCHEMAPT | |
| SCHEMBL7102141 | 0.87 | ALOX5 (0.76) | LMNANPC1RAB9ABCHEMAPT | |
| SCHEMBL5084154 | 0.85 | MAPT (0.78) | LMNANPC1RAB9ABCHEMAPT | |
| SCHEMBL31178767 | 0.85 | MAPT (0.64) | LMNANPC1RAB9ABCHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115400106-B | Application of natural compound and composition thereof in removing aging cells | 清华大学 | 2024-01-19 | — | — | CN | claimed |
| CN-115141621-A | Oil-based fracturing fluid, multi-stage fracturing method and method for online monitoring productivity of reservoir intervals | 中国石油化工股份有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-114557931-A | Whitening, moisturizing and anti-saccharification composition, preparation method and application thereof | 上海自易品牌管理有限公司 | 2022-05-31 | — | — | CN | claimed |
| CN-113908096-A | Whitening, moisturizing and anti-saccharification composition, preparation method and application thereof | 上海自易品牌管理有限公司 | 2022-01-11 | — | — | CN | claimed |
| CN-113924120-A | Compositions and methods for enhancing the musculoskeletal effects of one or more anabolic amino acids | 雀巢产品有限公司 | 2022-01-11 | — | — | CN | claimed |
| CN-112778208-A | Dihydropyrazole MurA enzyme inhibitor molecule and preparation method and application thereof | 中南民族大学 | 2021-05-11 | — | — | CN | claimed |
| EP-3562803-A1 | NOTCH INHIBITORS FOR USE IN THE TREATMENT OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA | Università degli Studi di Roma "La Sapienza" (IT) | 2019-11-06 | — | — | EP | claimed |
| CN-109400455-A | 2,5,2 ', 4 '-tetrahydroxys -4,5 '-dimethoxy chalcone and its extracting method and application | 滨州医学院 | 2019-03-01 | — | — | CN | claimed |
| WO-2018122689-A1 | NOTCH INHIBITORS FOR USE IN THE TREATMENT OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA | UNIVERSITÀ DEGLI STUDI DI ROMA "LA SAPIENZA" (IT) | 2018-07-05 | — | — | WO | claimed |
| CN-106831375-A | A kind of Chalcone Compounds with antitumor activity and its production and use | 哈尔滨医科大学 | 2017-06-13 | — | — | CN | claimed |
| CN-106748709-A | A kind of preparation method of the dimethoxy chalcone of 3,4,5 trimethoxy 3 ', 4 ' | 枣庄市润安制药新材料有限公司 | 2017-05-31 | — | — | CN | claimed |
| CN-106588613-A | Method for preparing 3,4,5-triethoxy-3',4'-dimethoxy chalcone | 枣庄市润安制药新材料有限公司 | 2017-04-26 | — | — | CN | claimed |
| CN-103936704-B | A kind of method preparing chrysin | KUNMING UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-09-30 | — | — | CN | claimed |
| US-7572831-B2 | Composition containing chalcone | ANGIOLAB, INC. (KR) | 2009-08-11 | — | — | US | claimed |
| CN-101448551-A | Use of chalcones for the treatment of viral disorders | JOHNSON & JOHNSON CONSUMER (US) | 2009-06-03 | — | — | CN | claimed |
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | claimed |
| US-20250255853-A1 | HUMAN THERAPEUTIC AGENTS | ANKH LIFE SCIENCES LIMITED (IE) | 2025-08-14 | — | — | US | disclosed |
| US-20240285592-A1 | HUMAN THERAPEUTIC AGENTS | ANKH LIFE SCIENCES LIMITED (IE) | 2024-08-29 | — | — | US | disclosed |
| WO-1993009764-A1 | COMBINED VIRUSTATIC ANTIMEDIATOR (COVAM) TREATMENT OF COMMON COLDS | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1993-05-27 | — | — | WO | disclosed |
| US-4863968-A | Methods of treating gout with chalcone derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240285592-A1 | HUMAN THERAPEUTIC AGENTS | INMT, NLN, MYC | LMNA 1873/4885NPC1 926/4885RAB9A 3068/4885 |
| US-20250255853-A1 | HUMAN THERAPEUTIC AGENTS | HASPIN, TIPARP, SHARPIN | LMNA 2978/4885NPC1 2233/4885RAB9A 1880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.