Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 6/20 | 0.33 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13720775 | 0.87 | MEN1 (0.35) | CYP2D6TAAR1MGLLMEN1KMT2A | |
| SCHEMBL4024525 | 0.87 | MEN1 (0.35) | CYP2D6TAAR1MGLLMEN1KMT2A | |
| SCHEMBL4024540 | 0.87 | MEN1 (0.35) | CYP2D6TAAR1MGLLMEN1KMT2A | |
| SCHEMBL4022240 | 0.86 | — | — | |
| SCHEMBL4749270 | 0.85 | KIF11 (0.35) | MGLLESR1ESR2KIF11GAA | |
| SCHEMBL4749258 | 0.85 | KIF11 (0.35) | MGLLESR1ESR2KIF11GAA | |
| SCHEMBL4338035 | 0.82 | KDM2B (0.41) | MGLLESR1ESR2MEN1KMT2A | |
| SCHEMBL4026114 | 0.82 | KDM2B (0.41) | MGLLESR1ESR2MEN1KMT2A | |
| SCHEMBL4338025 | 0.82 | KDM2B (0.41) | MGLLESR1ESR2MEN1KMT2A | |
| SCHEMBL4020327 | 0.82 | CPS1 (0.39) | MGLLMEN1KMT2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |