Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPS1 | P31327 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4024597 | 0.88 | KDM2B (0.45) | ALDH1A1MEN1KMT2A | |
| SCHEMBL4026485 | 0.87 | ALDH1A1 (0.48) | ALDH1A1TP53MEN1KMT2A | |
| SCHEMBL4022304 | 0.87 | TAS1R3 (0.39) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4025103 | 0.85 | KDM2B (0.41) | ALDH1A1KDM4EMCHR1MEN1KMT2A | |
| SCHEMBL4025770 | 0.84 | KDM2B (0.41) | ALDH1A1MEN1KMT2AMGLL | |
| SCHEMBL4022832 | 0.83 | KDM2B (0.43) | KDM4EMEN1KMT2A | |
| SCHEMBL4027142 | 0.82 | CYP2D6 (0.34) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4027984 | 0.82 | TAS1R3 (0.37) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL4026436 | 0.81 | KDM2B (0.42) | ALDH1A1MCHR1MEN1KMT2A | |
| SCHEMBL4019728 | 0.81 | TAS1R3 (0.36) | ALDH1A1MEN1KMT2AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |