Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4027100 | 0.86 | LMNA (0.37) | LMNARIPK1 | |
| SCHEMBL1447502 | 0.77 | HTT (0.40) | LMNARIPK1 | |
| SCHEMBL3551490 | 0.71 | TP53 (0.41) | LMNA | |
| SCHEMBL4027824 | 0.66 | LMNA (0.45) | LMNAOPRM1RIPK1 | |
| SCHEMBL1448022 | 0.66 | LMNA (0.37) | LMNARIPK1 | |
| SCHEMBL17749326 | 0.65 | MTNR1B (0.45) | — | |
| SCHEMBL4509021 | 0.65 | LMNA (0.39) | LMNA | |
| SCHEMBL6596993 | 0.64 | NPC1 (0.35) | LMNA | |
| SCHEMBL1447382 | 0.64 | LMNA (0.54) | LMNAOPRM1 | |
| SCHEMBL4251064 | 0.63 | LMNA (0.52) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485375-B1 | PYRIMIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2009-06-17 | — | — | EP | disclosed |