Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020283 | 0.90 | KDM1A (0.34) | KCNH2MCHR1KDM1AKDM2BMGLL | |
| SCHEMBL4020432 | 0.88 | KCNH2 (0.33) | MEN1KMT2AMAPK1KCNH2MCHR1 | |
| SCHEMBL13721487 | 0.86 | OPRM1 (0.35) | MEN1KMT2AMAPK1KCNH2MCHR1 | |
| SCHEMBL4028041 | 0.86 | OPRM1 (0.35) | MEN1KMT2AMAPK1KCNH2MCHR1 | |
| SCHEMBL4028045 | 0.86 | OPRM1 (0.35) | MEN1KMT2AMAPK1KCNH2MCHR1 | |
| SCHEMBL4022053 | 0.85 | MGLL (0.36) | MEN1KMT2AMAPK1KDM2BMGLL | |
| SCHEMBL4751548 | 0.84 | OPRM1 (0.34) | MEN1KMT2AMAPK1KCNH2MCHR1 | |
| SCHEMBL4772539 | 0.84 | OPRM1 (0.34) | MEN1KMT2AMAPK1KCNH2MCHR1 | |
| SCHEMBL4751549 | 0.84 | OPRM1 (0.34) | MEN1KMT2AMAPK1KCNH2MCHR1 | |
| SCHEMBL4022438 | 0.82 | KDM1A (0.33) | MEN1KMT2AMAPK1KCNH2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |