Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | CDC7 | O00311 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.47 |
| ▸ | PLK4 | O00444 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | MARK3 | P27448 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856825 | 0.89 | TAAR1 (0.50) | HPGDSPARP1MAP4K4CDC7CHEK2 | |
| SCHEMBL4026875 | 0.88 | BCAT2 (0.61) | PARP1BCAT2HTT | |
| SCHEMBL30463456 | 0.88 | BCAT2 (0.61) | PARP1BCAT2HTT | |
| SCHEMBL3632646 | 0.86 | BCAT2 (0.65) | HPGDSPARP1MAP4K4CDC7CHEK2 | |
| SCHEMBL29818012 | 0.86 | BCAT2 (0.65) | HPGDSPARP1MAP4K4CDC7CHEK2 | |
| SCHEMBL17796982 | 0.84 | DCLRE1B (0.53) | CHEK2PLK4AURKADAPK3CDK1 | |
| SCHEMBL31585756 | 0.84 | DCLRE1B (0.53) | CHEK2PLK4AURKADAPK3CDK1 | |
| SCHEMBL5616629 | 0.84 | IKBKB (0.51) | CDC7GSK3AGSK3BBCAT2JAK2 | |
| SCHEMBL20509706 | 0.84 | HPGDS (0.44) | HPGDSPARP1MAP4K4CDC7CHEK2 | |
| SCHEMBL28203761 | 0.82 | KMT2A (0.48) | HPGDSMAP4K4CDC7CHEK2PLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252140-B1 | PYRROLECARBOXAMIDES AND PYRROLETHIOAMIDES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-05-13 | — | — | EP | claimed |