Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.61 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.51 |
| ▸ | GRN | P28799 | 1/20 | 0.49 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15623775 | 0.98 | ALDH1A1 (0.62) | PLA2G2APLA2G5ALDH1A1MEN1KMT2A | |
| SCHEMBL11676490 | 0.93 | PLA2G2A (0.72) | PLA2G2APLA2G5ALDH1A1MEN1KMT2A | |
| SCHEMBL542910 | 0.93 | PLA2G2A (0.72) | PLA2G2APLA2G5ALDH1A1MEN1KMT2A | |
| SCHEMBL7325048 | 0.93 | PLA2G2A (0.72) | PLA2G2APLA2G5ALDH1A1MEN1KMT2A | |
| SCHEMBL23833964 | 0.93 | PLA2G2A (0.72) | PLA2G2APLA2G5ALDH1A1MEN1KMT2A | |
| SCHEMBL25183155 | 0.93 | PLA2G2A (0.72) | PLA2G2APLA2G5ALDH1A1MEN1KMT2A | |
| SCHEMBL19200047 | 0.93 | ALDH1A1 (0.58) | PLA2G2APLA2G5ALDH1A1MEN1KMT2A | |
| SCHEMBL8006368 | 0.93 | PLA2G2A (0.72) | PLA2G2APLA2G5ALDH1A1MEN1KMT2A | |
| SCHEMBL22923660 | 0.93 | PLA2G2A (0.55) | PLA2G2APLA2G5ALDH1A1MEN1KMT2A | |
| SCHEMBL5657458 | 0.93 | PLA2G2A (0.55) | PLA2G2APLA2G5ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010142-A2 | POLYESTERAMIDE PLATFORM FOR SITE SPECIFIC DRUG DELIVERY | Abbott Cardiovascular Systems, Inc. (US) | 2009-01-07 | — | — | EP | disclosed |
| WO-2008076771-A2 | COATINGS OF ACRYLAMIDE-BASED COPOLYMERS | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2008-06-26 | — | — | WO | disclosed |
| WO-2007146228-A2 | ELASTIN-BASED COPOLYMERS | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007123872-A2 | POLYESTERAMIDE PLATFORM FOR SITE SPECIFIC DRUG DELIVERY | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2007-11-01 | — | — | WO | disclosed |