Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.55 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.55 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.53 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22923660 | 1.00 | PLA2G2A (0.55) | PLA2G2APLA2G5NOD1ALDH1A1FOLH1 | |
| SCHEMBL4027352 | 0.93 | PLA2G2A (0.61) | PLA2G2APLA2G5NOD1ALDH1A1FOLH1 | |
| SCHEMBL15623775 | 0.91 | ALDH1A1 (0.62) | PLA2G2APLA2G5NOD1ALDH1A1FOLH1 | |
| SCHEMBL11676490 | 0.87 | PLA2G2A (0.72) | PLA2G2APLA2G5NOD1ALDH1A1PLA2G10 | |
| SCHEMBL542910 | 0.87 | PLA2G2A (0.72) | PLA2G2APLA2G5NOD1ALDH1A1PLA2G10 | |
| SCHEMBL23833964 | 0.87 | PLA2G2A (0.72) | PLA2G2APLA2G5NOD1ALDH1A1PLA2G10 | |
| SCHEMBL19200047 | 0.87 | ALDH1A1 (0.58) | PLA2G2APLA2G5NOD1ALDH1A1FOLH1 | |
| SCHEMBL7325048 | 0.87 | PLA2G2A (0.72) | PLA2G2APLA2G5NOD1ALDH1A1PLA2G10 | |
| SCHEMBL4741208 | 0.87 | PLA2G2A (0.72) | PLA2G2APLA2G5NOD1ALDH1A1PLA2G10 | |
| SCHEMBL25183155 | 0.87 | PLA2G2A (0.72) | PLA2G2APLA2G5NOD1ALDH1A1PLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109364-B2 | Group of anti-cancer compounds with specific structure and their production method | YANG ZHENHUA | 2006-09-19 | — | — | US | claimed |
| US-20040034242-A1 | Group of anti-cancer compounds with specific structure and their production method | YANG ZHENHUA (US) | 2004-02-19 | — | — | US | claimed |
| US-7109364-B2 | Group of anti-cancer compounds with specific structure and their production method | YANG ZHENHUA | 2006-09-19 | — | — | US | disclosed |
| EP-1259470-A4 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | YANG ZHENHUA (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20040034242-A1 | Group of anti-cancer compounds with specific structure and their production method | YANG ZHENHUA (US) | 2004-02-19 | — | — | US | disclosed |
| EP-1259470-A2 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | Yang, Zhenhua (US) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001059067-A2 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | YANG ZHENHUA (US) | 2001-08-16 | — | — | WO | disclosed |