SCHEMBL4820665

SCHEMBL4820665

CCCCCc1ccc(-c2ccc(C)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 7/20 0.59
HSD17B10 Q99714 3/20 0.59
TSHR P16473 1/20 0.59
ALDH1A1 P00352 4/20 0.58
MEN1 O00255 2/20 0.58
MAPT P10636 2/20 0.58
KMT2A Q03164 2/20 0.58
RARA P10276 1/20 0.58
MTOR P42345 1/20 0.58
RAB9A P51151 2/20 0.56
NPC1 O15118 1/20 0.56
ATM Q13315 1/20 0.56
ESR1 P03372 2/20 0.55
ADRA2A P08913 2/20 0.55
ADORA3 P0DMS8 2/20 0.55
TACR2 P21452 2/20 0.55
SLC6A2 P23975 2/20 0.55
SLC6A4 P31645 2/20 0.55
SLC6A3 Q01959 2/20 0.55
KDM4E B2RXH2 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30577318 0.98 HSD17B10 (0.62) RARBHSD17B10TSHRALDH1A1MEN1
SCHEMBL28385904 0.98 HSD17B10 (0.62) RARBHSD17B10TSHRALDH1A1MEN1
SCHEMBL2492800 0.93 RARB (0.58) RARBHSD17B10TSHRALDH1A1MEN1
SCHEMBL392911 0.93 ESR1 (0.61) HSD17B10ALDH1A1RAB9ANPC1ATM
SCHEMBL9678943 0.91 ESR1 (0.65) HSD17B10TSHRALDH1A1ESR1ADRA2A
Octane SCHEMBL9724037 0.91 ESR1 (0.65) HSD17B10TSHRALDH1A1ESR1ADRA2A
SCHEMBL396014 0.91 ESR1 (0.65) HSD17B10TSHRALDH1A1ESR1ADRA2A
SCHEMBL21963890 0.91 ESR1 (0.65) HSD17B10TSHRALDH1A1ESR1ADRA2A
SCHEMBL168031 0.91 ESR1 (0.65) HSD17B10TSHRALDH1A1ESR1ADRA2A
SCHEMBL80498 0.91 ESR1 (0.65) HSD17B10TSHRALDH1A1ESR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119438433-A Based on UiO-66-F4Method for analyzing liquid crystal monomer in indoor dust by solid phase extraction-high performance liquid chromatography 北京工业大学 2025-02-14 CN claimed
WO-2023005682-A1 METHOD FOR ANALYZING TARGETED EXPOSURE GROUP OF ENVIRONMENTAL POLLUTANTS IN PLASMA, AND USE THEREOF 暨南大学 2023-02-02 WO claimed
US-7335405-B2 Nematic liquid crystal mixtures for use in bistable display devices NEMOPTIC (FR) 2008-02-26 US claimed
US-20060249708-A1 Nematic liquid crystal mixtures for use in bistable display devices CDC PROPRIETE INTELLECTUELLE (FR) 2006-11-09 US claimed
US-4198130-A Liquid crystal mixtures HOFFMANN-LA ROCHE INC. (US) 1980-04-15 US claimed
US-4180475-A POSITIVE ANISOTROPY OF DIELECTRIC CONSTANTS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1979-12-25 US claimed
CN-119555817-A Pretreatment method for efficiently extracting trace liquid crystal monomer from water based on membrane filtration technology 南京理工大学 2025-03-04 CN disclosed
WO-2023167325-A1 IMMOBILIZED PALLADIUM CATALYST AND METHOD FOR PRODUCING SAME, AND APPLICATION OF THIS CATALYST TO COUPLING REACTION 国立研究開発法人理化学研究所 2023-09-07 WO disclosed
CN-113671068-B Method for analyzing environmental pollutant targeted exposure group in blood plasma and application thereof 暨南大学 2023-01-24 CN disclosed
US-9624434-B2 Nematic liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2017-04-18 US disclosed
WO-2013038149-A1 OPTICAL DEVICE CAMBRIDGE ENTERPRISE LIMITED (GB) 2013-03-21 WO disclosed
US-20120022024-A1 ANTI-BACTERIAL COMPOSITIONS AND METHODS INCLUDING TARGETING VIRULENCE FACTORS OF STAPHYLOCOCCUS AUREUS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2012-01-26 US disclosed
US-7335405-B2 Nematic liquid crystal mixtures for use in bistable display devices NEMOPTIC (FR) 2008-02-26 US disclosed
US-20060249708-A1 Nematic liquid crystal mixtures for use in bistable display devices CDC PROPRIETE INTELLECTUELLE (FR) 2006-11-09 US disclosed
EP-0167912-B1 LIQUID CRYSTAL MIXTURES CONTAINING COMPOUNDS WITH A 4-ALKENYL OR 2Z-ALKENYL LATERAL CHAIN F. HOFFMANN-LA ROCHE AG (CH) 1990-01-03 EP disclosed
EP-0167912-A2 Liquid crystal mixtures containing compounds with a 4-alkenyl or 2Z-alkenyl lateral chain F. HOFFMANN-LA ROCHE AG (CH) 1986-01-15 EP disclosed
US-4198130-A Liquid crystal mixtures HOFFMANN-LA ROCHE INC. (US) 1980-04-15 US disclosed
US-4180475-A POSITIVE ANISOTROPY OF DIELECTRIC CONSTANTS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1979-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120022024-A1 ANTI-BACTERIAL COMPOSITIONS AND METHODS INCLUDING TARGETING VIRULENCE FACTORS OF STAPHYLOCOCCUS AUREUS CUTA, MMP8, CLPP RARB 3294/4885HSD17B10 3345/4885TSHR 4335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.