SCHEMBL402803

SCHEMBL402803

CC(=O)NC1COC(CO)[C@@H](C)[C@H]1OCc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.41
OGA O60502 2/20 0.41
KLK7 P49862 3/20 0.40
KLK5 Q9Y337 2/20 0.40
BCHE P06276 1/20 0.38
TACR2 P21452 1/20 0.38
ACACB O00763 2/20 0.37
HRAS P01112 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
LGALS8 O00214 1/20 0.36
ACACA Q13085 1/20 0.36
PDPK1 O15530 1/20 0.36
MTOR P42345 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26878951 0.91 L3MBTL1 (0.41) SLC6A2L3MBTL1OGAKLK7KLK5
SCHEMBL14363001 0.91 SLC6A2 (0.45) SLC6A2L3MBTL1OGAKLK7KLK5
SCHEMBL26879054 0.89 TP53 (0.42) SLC6A2L3MBTL1KLK7KLK5BCHE
SCHEMBL26879052 0.89 TP53 (0.42) SLC6A2L3MBTL1KLK7KLK5BCHE
SCHEMBL404432 0.88 LMNA (0.44) L3MBTL1KLK7KLK5BCHEACACB
SCHEMBL403009 0.85 L3MBTL1 (0.38) SLC6A2L3MBTL1OGAKLK7KLK5
SCHEMBL16211783 0.82 SLC6A2 (0.47) SLC6A2L3MBTL1KLK7KLK5BCHE
SCHEMBL23705084 0.82 TP53 (0.45) L3MBTL1KLK7KLK5BCHETACR2
SCHEMBL23705152 0.82 TP53 (0.45) L3MBTL1KLK7KLK5BCHETACR2
SCHEMBL14363003 0.81 LMNA (0.45) L3MBTL1KLK7KLK5BCHEACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120065153-A1 AZASUGAR DERIVATIVES, HEPARANASE INHIBITORS, METHOD FOR PREPARING SAME, COMPOSITIONS CONTAINING SAME, USE THEREOF SANOFI-AVENTIS (FR) 2012-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120065153-A1 AZASUGAR DERIVATIVES, HEPARANASE INHIBITORS, METHOD FOR PREPARING SAME, COMPOSITIONS CONTAINING SAME, USE THEREOF HPSE, HAAO, HEXD SLC6A2 2728/4885L3MBTL1 4789/4885OGA 76/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.