Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GYS1 | P13807 | 2/20 | 0.37 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.30 |
| ▸ | ABAT | P80404 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4945737 | 0.82 | POLB (0.40) | MAPTKDM4EGAAERN1 | |
| SCHEMBL29652066 | 0.69 | GPR35 (0.54) | S100A4GPR35GAAMCL1ERN1 | |
| SCHEMBL6016410 | 0.69 | ALDH1A1 (0.49) | MAPTKDM4EGAARECQL | |
| SCHEMBL15121520 | 0.68 | MEN1 (0.33) | GYS1MAPTKDM4EGRIN2DGRIN3B | |
| SCHEMBL7435964 | 0.66 | S100A4 (0.40) | GYS1S100A4GPR35MAPTKDM4E | |
| SCHEMBL70085 | 0.64 | GPR35 (0.59) | S100A4GPR35MAPTKDM4ERECQL | |
| SCHEMBL9448642 | 0.64 | ERN1 (0.53) | S100A4GPR35ERN1ALDH5A1ABAT | |
| SCHEMBL11344292 | 0.63 | GPR35 (0.42) | S100A4GPR35MAPTKDM4EGAA | |
| SCHEMBL4217610 | 0.63 | TSHR (0.43) | S100A4GPR35GRIN2DGRIN3BGRIN1 | |
| SCHEMBL28740174 | 0.63 | ALDH1A1 (0.54) | S100A4GPR35MCL1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027091-A1 | NEW PHARMACEUTICAL COMPOUNDS | BIAL - Portela & Ca., S.A. (PT) | 2009-02-25 | — | — | EP | claimed |
| WO-2007117165-A1 | NEW PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & CA, S.A. (PT) | 2007-10-18 | — | — | WO | claimed |