SCHEMBL4028253

SCHEMBL4028253

CN(Cc1cc(-c2cccnc2F)c(S(=O)(=O)c2cccc(C=O)c2)s1)C(=O)OC(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.31
GLS O94925 1/20 0.31
PDK2 Q15119 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3654948 0.88 F2 (0.35) F2GLSPDK2
SCHEMBL4120130 0.88 C1S (0.32)
SCHEMBL3647318 0.88 GLS (0.34) F2GLSPDK2
SCHEMBL3649517 0.88 NFE2L2 (0.38) F2
SCHEMBL4530415 0.88 PDK2 (0.32) GLSPDK2
SCHEMBL3651630 0.87 HTR2C (0.32) GLSPDK2
SCHEMBL4024383 0.86 RORC (0.35)
SCHEMBL3652358 0.84 GLS (0.32) F2GLSPDK2
Hydrochloric Acid SCHEMBL3645132 0.84 GLS (0.34) F2GLSPDK2
Hydrochloric Acid SCHEMBL3653183 0.83 F2 (0.34) F2GLSPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009041705-A9 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS TAKEDA PHARMACEUTICAL (JP) 2009-08-13 WO disclosed