Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.37 |
| ▸ | KLK7 | P49862 | 4/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL402935 | 0.83 | PDPK1 (0.37) | BCHETMEM97SIGMAR1GSTP1PDPK1 | |
| SCHEMBL21572017 | 0.83 | BCHE (0.44) | BCHETMEM97SIGMAR1KLK7KLK5 | |
| SCHEMBL402934 | 0.82 | TACR1 (0.38) | BCHESIGMAR1CYP2C19MAPTL3MBTL1 | |
| SCHEMBL14362931 | 0.78 | METAP2 (0.37) | BCHEMETAP2TMEM97SIGMAR1GSTP1 | |
| SCHEMBL402507 | 0.78 | METAP2 (0.35) | BCHEMETAP2POLBGAA | |
| SCHEMBL22965651 | 0.76 | BCHE (0.48) | BCHEMETAP2PDPK1MTORPOLB | |
| SCHEMBL10148625 | 0.76 | NT5E (0.39) | BCHETMEM97SIGMAR1L3MBTL1 | |
| SCHEMBL10148633 | 0.75 | L3MBTL1 (0.38) | BCHEMETAP2TMEM97SIGMAR1GSTP1 | |
| SCHEMBL7154490 | 0.75 | CA1 (0.52) | BCHEMETAP2POLBGAAL3MBTL1 | |
| SCHEMBL7150000 | 0.75 | CA1 (0.52) | BCHEMETAP2POLBGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065153-A1 | AZASUGAR DERIVATIVES, HEPARANASE INHIBITORS, METHOD FOR PREPARING SAME, COMPOSITIONS CONTAINING SAME, USE THEREOF | SANOFI-AVENTIS (FR) | 2012-03-15 | — | — | US | disclosed |
| US-20070270354-A1 | Azasugar derivatives, heparanase inhibitors, method for preparing same, compositions containing same, use thereof | SANOFI-AVENTIS (FR) | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065153-A1 | AZASUGAR DERIVATIVES, HEPARANASE INHIBITORS, METHOD FOR PREPARING SAME, COMPOSITIONS CONTAINING SAME, USE THEREOF | HPSE, HAAO, HEXD | BCHE 1419/4885METAP2 1897/4885TMEM97 2432/4885 |
| US-20070270354-A1 | Azasugar derivatives, heparanase inhibitors, method for preparing same, compositions containing same, use thereof | HPSE, HAAO, HEXD | BCHE 1409/4885METAP2 1858/4885TMEM97 2447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.