Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.52 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11439198 | 0.86 | KMT2A (0.63) | SMN1; SMN2ALDH1A1NPC1RAB9ACA1 | |
| SCHEMBL20711657 | 0.85 | PTGS2 (0.57) | PTGS2SMN1; SMN2KDM4EGAAALDH1A1 | |
| SCHEMBL5072981 | 0.84 | ALDH1A1 (0.48) | PTGS2SMN1; SMN2ALDH1A1PARP10PARP4 | |
| SCHEMBL20984200 | 0.84 | PTGS2 (0.64) | PTGS2SMN1; SMN2KDM4EGAAALDH1A1 | |
| SCHEMBL5075214 | 0.83 | PEPD (0.52) | PTGS2SMN1; SMN2KDM4EGAAALDH1A1 | |
| SCHEMBL425146 | 0.82 | PTGS2 (0.62) | PTGS2SMN1; SMN2KDM4EGAAALDH1A1 | |
| SCHEMBL2831390 | 0.82 | PTGS2 (0.67) | PTGS2SMN1; SMN2KDM4EGAAALDH1A1 | |
| SCHEMBL14557595 | 0.81 | PTGS2 (0.57) | PTGS2SMN1; SMN2KDM4EGAAALDH1A1 | |
| SCHEMBL455046 | 0.81 | GAA (0.54) | PTGS2SMN1; SMN2KDM4EGAAALDH1A1 | |
| SCHEMBL10516397 | 0.81 | PRSS1 (0.52) | PTGS2SMN1; SMN2KDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558756-A | 2-aryl-2, 3-dihydro-4 (1H) -quinolinone semicarbazone compound and application thereof | 沈阳药科大学 | 2018-09-21 | — | — | CN | claimed |
| EP-1442026-B9 | TRIAZOLE DERIVATIVES AS CYCLOOXYGENASE (COX) INHIBITORS | ASTELLAS PHARMA INC (JP) | 2009-11-18 | — | — | EP | disclosed |
| EP-1442026-B1 | TRIAZOLE DERIVATIVES AS CYCLOOXYGENASE (COX) INHIBITORS | ASTELLAS PHARMA INC (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-7448533-B2 | Medical image file management system and medical image film | FUJIFILM CORPORATION (JP) | 2008-11-11 | — | — | US | disclosed |
| US-7448533-B2 | Medical image file management system and medical image film | FUJIFILM CORPORATION (JP) | 2008-11-11 | — | — | US | disclosed |
| US-7410745-B2 | Photothermographic material and image forming method using same | FUJIFILM CORPORATION (JP) | 2008-08-12 | — | — | US | disclosed |
| US-7410745-B2 | Photothermographic material and image forming method using same | FUJIFILM CORPORATION (JP) | 2008-08-12 | — | — | US | disclosed |
| US-7253826-B2 | Thermal development apparatus | FUJIFILM CORPORATION (JP) | 2007-08-07 | — | — | US | disclosed |
| US-7253826-B2 | Thermal development apparatus | FUJIFILM CORPORATION (JP) | 2007-08-07 | — | — | US | disclosed |
| US-7157665-B2 | Heat development apparatus and method | FUJI PHOTO FILM CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |
| US-20030191155-A1 | Triazole derivatives | ASTELLAS PHARMA INC. (JP) | 2003-10-09 | — | — | US | disclosed |
| WO-2003040110-A1 | TRIAZOLE DERIVATIVES AS CYCLOOXYGENASE (COX) INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-15 | — | — | WO | disclosed |
| EP-0797098-B1 | Method for stabilizing bilirubin in control sera and calibrators | ROCHE DIAGNOSTICS GMBH (DE) | 2002-10-02 | — | — | EP | disclosed |
| US-5854073-A | Stabilization of bilirubin in control sera and calibrators | BOHRINGER MANNHEIM GMBH (DE) | 1998-12-29 | — | — | US | disclosed |
| US-5726314-A | ACETYLCHOLINESTERASE INHIBITORS AS NERVE AGENT ANTIDOTES | GEORGIA TECH RESEARCH CORP. (US) | 1998-03-10 | — | — | US | disclosed |
| US-5714615-A | ACETYLCHOLINESTERASE ENZYME INHIBITOR, STIMULATE NICOTINIC RECEPTORS IN CENTRAL NERVOUS SYSTEM | GEORGIA TECH RESEARCH CORPORATION (US) | 1998-02-03 | — | — | US | disclosed |
| EP-0797098-A2 | Method for stabilizing bilirubin in control sera and calibrators | Roche Diagnostics GmbH (DE) | 1997-09-24 | — | — | EP | disclosed |
| WO-1995021822-A1 | PYRIDINIUM COMPOUNDS | GEORGIA TECH RESEARCH CORPORATION (US) | 1995-08-17 | — | — | WO | disclosed |
| US-4297271-A | CHROMAGEN IN A DIAGNOSTIC TEST FOR FECAL BLOOD; CHROMATOGRAPHY | BOEHRINGER MANNHEIM GMBH (DE) | 1981-10-27 | — | — | US | disclosed |
| US-4219336-A | HYDROGEN PEROXIDE, GUAIACONIC ACID | BOEHRINGER MANNHEIM GMBH (DE) | 1980-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191155-A1 | Triazole derivatives | CBR1, CBR3, CYP1B1 | PTGS2 2680/4885SMN1; SMN2 4243/4885KDM4E 3034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.