SCHEMBL425146

SCHEMBL425146

COc1ccc(NNC(C)=O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.62
CYP3A4 P08684 1/20 0.59
ALOX5 P09917 1/20 0.59
TSHR P16473 1/20 0.59
SMN1; SMN2 Q16637 3/20 0.57
KDM4E B2RXH2 2/20 0.57
GAA P10253 2/20 0.57
ALDH1A1 P00352 1/20 0.57
NPC1 O15118 4/20 0.57
RAB9A P51151 4/20 0.57
P2RX7 Q99572 1/20 0.54
IDO1 P14902 1/20 0.54
TP53 P04637 1/20 0.52
ALOX15 P16050 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.50
MAPT P10636 2/20 0.50
THRB P10828 1/20 0.50
MAPK1 P28482 1/20 0.50
RECQL P46063 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11684016 0.86 FFAR1 (0.62) PTGS2SMN1; SMN2KDM4EGAAALDH1A1
SCHEMBL20984200 0.86 PTGS2 (0.64) PTGS2SMN1; SMN2KDM4EGAAALDH1A1
SCHEMBL2831390 0.84 PTGS2 (0.67) PTGS2SMN1; SMN2KDM4EGAAALDH1A1
SCHEMBL4028705 0.82 PTGS2 (0.60) PTGS2SMN1; SMN2KDM4EGAAALDH1A1
SCHEMBL28713032 0.81 PTGS2 (0.58) PTGS2CYP3A4TSHRSMN1; SMN2KDM4E
SCHEMBL27941644 0.79 RAB9A (0.72) PTGS2TSHRSMN1; SMN2KDM4ENPC1
SCHEMBL14518056 0.79 L3MBTL1 (0.63) PTGS2SMN1; SMN2KDM4EGAAALDH1A1
SCHEMBL20711657 0.79 PTGS2 (0.57) PTGS2SMN1; SMN2KDM4EGAAALDH1A1
SCHEMBL2887835 0.79 PTGS2 (0.57) PTGS2SMN1; SMN2KDM4EGAAALDH1A1
SCHEMBL14557595 0.79 PTGS2 (0.57) PTGS2SMN1; SMN2KDM4EGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114230507-A Preparation method of 5-methoxytryptamine 阜阳欣奕华制药科技有限公司 2022-03-25 CN claimed
US-7115676-B2 Adhesive compositions for bonding passive substrates HENKEL CORPORATION (US) 2006-10-03 US claimed
US-20030217808-A1 Adhesive compositions for bonding passive substrates Henkel IP & Holding GmbH (DE) 2003-11-27 US claimed
EP-1285037-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS Henkel Loctite Corporation (US) 2003-02-26 EP claimed
WO-2001088050-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS HENKEL LOCTITE CORPORATION (US) 2001-11-22 WO claimed
EP-4714992-A1 POLYTETRAMETHYLENE GLYCOL-BASED (METH)ACRYLATE COMPOUND Cemedine Co., Ltd. (JP) 2026-03-25 EP disclosed
CN-115894326-B 2, 3-Hydrogen substituted aminoindole derivative, preparation method and application thereof 佛山大学 2025-02-11 CN disclosed
WO-2024242005-A1 POLYTETRAMETHYLENE GLYCOL-BASED (METH)ACRYLATE COMPOUND セメダイン株式会社 2024-11-28 WO disclosed
CN-114230507-B Preparation method of 5-methoxy tryptamine 阜阳欣奕华制药科技有限公司 2024-11-12 CN disclosed
CN-115894326-A 2,3-hydrogen substituted aminoindole derivative, preparation method and application thereof 佛山科学技术学院 2023-04-04 CN disclosed
CN-114230507-A Preparation method of 5-methoxytryptamine 阜阳欣奕华制药科技有限公司 2022-03-25 CN disclosed
CN-109467528-B Synthesis method of 1-aminoindole derivative 佛山科学技术学院 2020-11-06 CN disclosed
US-4912011-A Polymerizable compound and color image forming substances are encapsulated FUJI PHOTO FILM CO., LTD. (JP) 1990-03-27 US disclosed
US-4910115-A Mixing of reducing agent, silver halide, a polymerizable compound and a (keto)coumarin THE MEAD CORPORATION (US) 1990-03-20 US disclosed
US-4629676-A DRY PROCESSING FUJI PHOTO FILM CO., LTD. (JP) 1986-12-16 US disclosed
EP-0203613-A2 Light-sensitive material containing microcapsules and image-recording method using the same FUJI PHOTO FILM CO., LTD. (JP) 1986-12-03 EP disclosed
EP-0174634-A2 Image forming method FUJI PHOTO FILM CO., LTD. (JP) 1986-03-19 EP disclosed
US-4321349-A Accelerator for curable compositions LOCTITE CORPORATION (US) 1982-03-23 US disclosed
US-4287330-A Accelerator for curable compositions LOCTITE CORPORATION (US) 1981-09-01 US disclosed
US-4180640-A HYDRAZIDE DERIVATIVES LOCTITE CORPORATION (US) 1979-12-25 US disclosed