Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 8/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776307 | 0.87 | KDM2B (0.37) | MCHR1KDM2BKMT2AHTTDRD4 | |
| SCHEMBL13721097 | 0.86 | KDM2B (0.37) | MCHR1KCNH2KDM2BKMT2AHTT | |
| SCHEMBL4022391 | 0.86 | KDM2B (0.37) | MCHR1KCNH2KDM2BKMT2AHTT | |
| SCHEMBL4022390 | 0.86 | KDM2B (0.37) | MCHR1KCNH2KDM2BKMT2AHTT | |
| SCHEMBL4022340 | 0.83 | KDM1A (0.31) | MCHR1KCNH2KDM2B | |
| SCHEMBL4780092 | 0.82 | KDM2B (0.43) | KDM2BKMT2AHTTDRD4L3MBTL1 | |
| SCHEMBL4749161 | 0.80 | KDM2B (0.38) | MCHR1KCNH2KDM2BKMT2AHTT | |
| SCHEMBL13721487 | 0.80 | OPRM1 (0.35) | MCHR1KCNH2KDM2BKMT2AMEN1 | |
| SCHEMBL4028045 | 0.80 | OPRM1 (0.35) | MCHR1KCNH2KDM2BKMT2AMEN1 | |
| SCHEMBL4028041 | 0.80 | OPRM1 (0.35) | MCHR1KCNH2KDM2BKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | disclosed |
| US-20070161674-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2007-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161674-A1 | Certain chemical entities, compositions, and methods | TP53, VHL, RB1 | MCHR1 3670/4885KCNH2 3099/4885KDM2B 3090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.