Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 5/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4025759 | 0.91 | KDM2B (0.35) | KDM2BMCHR1NPSR1KMT2AHTT | |
| SCHEMBL4021139 | 0.83 | KDM2B (0.43) | KDM2BMC4RMCHR1NPSR1KMT2A | |
| SCHEMBL4776307 | 0.82 | KDM2B (0.37) | KDM2BMCHR1KMT2AHTTDRD2 | |
| SCHEMBL4026436 | 0.82 | KDM2B (0.42) | KDM2BMC4RMCHR1NPSR1KMT2A | |
| SCHEMBL4020026 | 0.82 | KDM2B (0.42) | KDM2BMC4RMCHR1NPSR1KMT2A | |
| SCHEMBL4029300 | 0.80 | MCHR1 (0.36) | KDM2BMCHR1NPSR1KMT2AHTT | |
| SCHEMBL4749342 | 0.80 | KDM2B (0.40) | KDM2BMC4RMCHR1NPSR1KMT2A | |
| SCHEMBL4024597 | 0.79 | KDM2B (0.45) | KDM2BNPSR1KMT2AHTTDRD2 | |
| SCHEMBL4021398 | 0.79 | KDM2B (0.45) | KDM2BNPSR1KMT2AHTTDRD2 | |
| SCHEMBL4749206 | 0.79 | KDM2B (0.42) | KDM2BMC4RKMT2ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | claimed |