Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035244 | 0.85 | SCN8A (0.39) | SCN8ASCN10ANOTUMMTNR1AMTNR1B | |
| SCHEMBL3935484 | 0.77 | HTR2A (0.41) | SCN8ASCN10ANOTUMMTNR1AMTNR1B | |
| SCHEMBL4029370 | 0.76 | HTR1A (0.42) | SCN8ASCN10ANOTUMMTNR1AMTNR1B | |
| SCHEMBL5149356 | 0.74 | KDM4E (0.38) | KDM4ECNR2MEN1KMT2A | |
| SCHEMBL5149347 | 0.74 | KDM4E (0.38) | KDM4ECNR2MEN1KMT2A | |
| SCHEMBL17242338 | 0.71 | KCNH2 (0.48) | SLC6A4MPO | |
| SCHEMBL4035537 | 0.71 | SCN8A (0.37) | SCN8ASCN10ANOTUMMTNR1AMTNR1B | |
| SCHEMBL4031716 | 0.70 | SCN8A (0.36) | SCN8ASCN10ANOTUMMTNR1AMTNR1B | |
| SCHEMBL4034238 | 0.69 | SCN8A (0.34) | SCN8ASCN10AKDM4ENOTUMMTNR1A | |
| SCHEMBL4033961 | 0.68 | MPO (0.41) | SCN8ASCN10AHTR1ASPRSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019102-A1 | Alkylacetylene substituted Acyltryptophanols | Bayer Schering Pharma AG (DE) | 2009-01-28 | — | — | EP | disclosed |