Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SSTR2 | P30874 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5149347 | 1.00 | KDM4E (0.38) | KDM4EMAPK1MAPTMEN1KMT2A | |
| SCHEMBL4035244 | 0.89 | SCN8A (0.39) | ALDH1A1 | |
| SCHEMBL4032359 | 0.87 | KMT2A (0.47) | MAPTMEN1KMT2ACNR2FFAR1 | |
| SCHEMBL4032356 | 0.87 | KMT2A (0.47) | MAPTMEN1KMT2ACNR2FFAR1 | |
| SCHEMBL5149435 | 0.81 | MEN1 (0.39) | KDM4EMEN1KMT2AALDH1A1CNR2 | |
| SCHEMBL5149423 | 0.81 | MEN1 (0.39) | KDM4EMEN1KMT2AALDH1A1CNR2 | |
| SCHEMBL5172047 | 0.80 | CCKBR (0.44) | KDM4EMAPK1MAPTMEN1KMT2A | |
| SCHEMBL4599804 | 0.80 | CCKBR (0.44) | KDM4EMAPK1MAPTMEN1KMT2A | |
| SCHEMBL4632723 | 0.76 | ALOX5 (0.41) | KDM4EMAPK1MAPTMEN1KMT2A | |
| SCHEMBL4632727 | 0.76 | ALOX5 (0.41) | KDM4EMAPK1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | FSHR, NPY1R, NPY2R | KDM4E 2399/4885MAPK1 3998/4885MAPT 4047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.