Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | MT-CO2 | P00403 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168295 | 0.83 | PTGS2 (0.75) | PTGS2PTGS1MT-CO2CA12CA1 | |
| SCHEMBL4028144 | 0.82 | PTGS2 (0.50) | PTGS2PTGS1ESR1ESR2MT-CO2 | |
| SCHEMBL6169671 | 0.78 | PTGS2 (0.46) | PTGS2PTGS1ESR1ESR2MT-CO2 | |
| SCHEMBL14163954 | 0.78 | ESR1 (0.68) | PTGS2PTGS1ESR1ESR2MT-CO2 | |
| SCHEMBL6167767 | 0.78 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL22827965 | 0.77 | PTGS2 (0.56) | PTGS2PTGS1ESR1ESR2MT-CO2 | |
| SCHEMBL22827980 | 0.77 | ESR1 (0.49) | PTGS2PTGS1ESR1ESR2MT-CO2 | |
| SCHEMBL4807004 | 0.77 | ESR1 (0.56) | PTGS2PTGS1ESR1ESR2MT-CO2 | |
| SCHEMBL22827973 | 0.74 | PTGS1 (0.46) | PTGS2PTGS1ESR1ESR2MT-CO2 | |
| SCHEMBL8476862 | 0.74 | PTGS2 (0.59) | PTGS2PTGS1ESR1ESR2MT-CO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492773-B1 | 4-(HETEROCYCLYL)-BENZENESULFOXIMINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | CADILA HEALTHCARE LTD (IN) | 2009-02-04 | — | — | EP | disclosed |
| US-7348342-B2 | Heterocyclic compounds process for their preparation and pharmaceutical compositions containing them and their use in medicine | CADILA HEALTHCARE LIMITED (IN) | 2008-03-25 | — | — | US | disclosed |
| US-20050277678-A1 | Heterocyclic compounds process for their preparation and pharmceutical compositions containing them and their use in medicine | CADILA HEALTHCARE LIMITED (IN) | 2005-12-15 | — | — | US | disclosed |
| EP-1492773-A2 | 4-(HETEROCYCLYL)-BENZENESULFOXIMINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | CADILA HEALTHCARE LTD. (IN) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003087062-A2 | 4-(HETEROCYCLYL)-BENZENESULFOXIMINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | CADILA HEALTHCARE LIMITED (IN) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277678-A1 | Heterocyclic compounds process for their preparation and pharmceutical compositions containing them and their use in medicine | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HPGDS, LTC4S | PTGS2 27/4885PTGS1 22/4885ESR1 4627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.