SCHEMBL402978

SCHEMBL402978

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nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ FGF1 P05230 1/20 0.31
▸ FGF2 P09038 1/20 0.31
▸ F10 P00742 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL404418 0.83 FGF1 (0.32) FGF1FGF2
SCHEMBL15883971 0.82 FGF1 (0.34) FGF1FGF2F10
SCHEMBL6123938 0.82 FGF1 (0.34) FGF1FGF2F10
SCHEMBL18174832 0.81 SERPINC1 (0.36) FGF1FGF2F10
SCHEMBL15883973 0.81 SERPINC1 (0.36) FGF1FGF2F10
SCHEMBL12346246 0.80 F10 (0.35) FGF1FGF2F10
SCHEMBL14362999 0.78 FGF1 (0.33) FGF1FGF2F10
SCHEMBL404030 0.78 FGF1 (0.33) FGF1FGF2F10
SCHEMBL12895304 0.72 F10 (0.35) F10
SCHEMBL730705 0.72 F10 (0.35) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120065153-A1 AZASUGAR DERIVATIVES, HEPARANASE INHIBITORS, METHOD FOR PREPARING SAME, COMPOSITIONS CONTAINING SAME, USE THEREOF SANOFI-AVENTIS (FR) 2012-03-15 — — US disclosed
US-20070270354-A1 Azasugar derivatives, heparanase inhibitors, method for preparing same, compositions containing same, use thereof SANOFI-AVENTIS (FR) 2007-11-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120065153-A1 AZASUGAR DERIVATIVES, HEPARANASE INHIBITORS, METHOD FOR PREPARING SAME, COMPOSITIONS CONTAINING SAME, USE THEREOF HPSE, HAAO, HEXD FGF1 959/4885FGF2 1169/4885F10 181/4885
US-20070270354-A1 Azasugar derivatives, heparanase inhibitors, method for preparing same, compositions containing same, use thereof HPSE, HAAO, HEXD FGF1 926/4885FGF2 1136/4885F10 174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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