Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
| ▸ | GABRE | P78334 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4026100 | 0.82 | — | — | |
| SCHEMBL4026102 | 0.82 | — | — | |
| SCHEMBL69773 | 0.78 | NOTUM (0.44) | NOTUMALDH1A1ALOX15L3MBTL1CYP1A2 | |
| SCHEMBL23772097 | 0.74 | KDM4E (0.39) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL970535 | 0.74 | HSP90AB1 (0.37) | PPARGPPARAALDH1A1L3MBTL1 | |
| SCHEMBL5176186 | 0.72 | ALDH1A1 (0.41) | NOTUMALDH1A1ALOX15CYP1A2 | |
| SCHEMBL3669707 | 0.70 | NOTUM (0.48) | NOTUMALDH1A1ALOX15GABRPGABRD | |
| SCHEMBL30516181 | 0.69 | HMGB1 (0.39) | ALDH1A1ALOX15GABRPGABRDGABRA1 | |
| SCHEMBL5175113 | 0.68 | KDM4E (0.41) | NOTUMALDH1A1ALOX15L3MBTL1GABRP | |
| SCHEMBL4033104 | 0.68 | NOTUM (0.33) | NOTUMALDH1A1ALOX15CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252140-B1 | PYRROLECARBOXAMIDES AND PYRROLETHIOAMIDES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-05-13 | — | — | EP | claimed |