Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HAAO | P46952 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 3/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69773 | 0.85 | NOTUM (0.44) | NOTUMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13790595 | 0.81 | SMN1; SMN2 (0.38) | NOTUMKDM4EALDH1A1GAACYP1A2 | |
| SCHEMBL4030620 | 0.79 | NOTUM (0.32) | NOTUM | |
| SCHEMBL5176186 | 0.78 | ALDH1A1 (0.41) | NOTUMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4029538 | 0.76 | — | — | |
| SCHEMBL13757990 | 0.76 | BRD4 (0.42) | KDM4EGAA | |
| SCHEMBL21428265 | 0.76 | NR4A2 (0.43) | KDM4EALDH1A1HSD17B10GAAMYC | |
| SCHEMBL7097879 | 0.74 | NOTUM (0.41) | NOTUMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5175113 | 0.74 | KDM4E (0.41) | NOTUMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9611418 | 0.74 | NOTUM (0.50) | NOTUMKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252140-B1 | PYRROLECARBOXAMIDES AND PYRROLETHIOAMIDES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-05-13 | — | — | EP | claimed |
| US-20230062975-A1 | HEPATITIS B CAPSID ASSEMBLY MODULATORS | SPRING MILL PHARMA, INC. | 2023-03-02 | — | — | US | disclosed |
| US-20230062975-A1 | HEPATITIS B CAPSID ASSEMBLY MODULATORS | SPRING MILL PHARMA, INC. | 2023-03-02 | — | — | US | disclosed |
| US-11566001-B2 | Hepatitis B capsid assembly modulators | VenatoRx Pharmaceuticals, Inc. (US) | 2023-01-31 | — | — | US | disclosed |
| US-11566001-B2 | Hepatitis B capsid assembly modulators | VenatoRx Pharmaceuticals, Inc. (US) | 2023-01-31 | — | — | US | disclosed |
| US-20220298110-A1 | HEPATITIS B CAPSID ASSEMBLY MODULATORS | SPRING MILL PHARMA, INC. | 2022-09-22 | — | — | US | disclosed |
| US-11247965-B2 | Hepatitis B capsid assembly modulators | VenatoRx Pharmaceuticals, Inc. (US) | 2022-02-15 | — | — | US | disclosed |
| CN-113056461-A | Arylsulfonyl pyrrole carboxamide derivatives as Kv3 potassium channel activators | H.隆德贝克有限公司 | 2021-06-29 | — | — | CN | disclosed |
| US-20210171439-A1 | HEPATITIS B CAPSID ASSEMBLY MODULATORS | VenatoRx Pharmaceuticals, Inc. (US) | 2021-06-10 | — | — | US | disclosed |
| US-11014881-B2 | Hepatitis B capsid assembly modulators | VenatoRx Pharmaceuticals, Inc. (US) | 2021-05-25 | — | — | US | disclosed |
| US-20090163488-A1 | FUSED HETEROCYCLE DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-25 | — | — | US | disclosed |
| EP-1252140-B1 | PYRROLECARBOXAMIDES AND PYRROLETHIOAMIDES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008150015-A1 | HETEROBICYCLIC COMPOUNDS AS KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-11 | — | — | WO | disclosed |
| US-7087638-B2 | Pyrrolecarboxamides and pyrrolethioamides as fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2006-08-08 | — | — | US | disclosed |
| CN-1255380-C | Pyrroleamide and pyrrolethioamide fungicides | SYNGENTA PARTICIPATIONS AG (CH) | 2006-05-10 | — | — | CN | disclosed |
| US-6806286-B2 | CONTROLLING PHYTOPATHOGENIC MICROORGANISMS FROM INFESTING PLANTS | SYNGENTA CROP PROTECTION, INC. | 2004-10-19 | — | — | US | disclosed |
| US-20040106521-A1 | Plant safening agents; | SYNGENTA CROP PROTECTION, INC. | 2004-06-03 | — | — | US | disclosed |
| US-20040049035-A1 | Pyrrolecarboxamides and pyrrolethioamides as fungicides | SYNGENTA CROP PROTECTION, INC. | 2004-03-11 | — | — | US | disclosed |
| CN-1427823-A | Pyrrolecarboxamides and pyrrolethioamides as fungicides | SYNGENTA PARTICIPATIONS AG (CH) | 2003-07-02 | — | — | CN | disclosed |
| US-4548696-A | 3,4-Disubstituted polypyrroles and articles of manufacture coated therewith | OLIN CORPORATION (US) | 1985-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230062975-A1 | HEPATITIS B CAPSID ASSEMBLY MODULATORS | HAVCR2, COPB1, HDLBP | NOTUM 4325/4885KDM4E 3751/4885ALDH1A1 3850/4885 |
| US-11566001-B2 | Hepatitis B capsid assembly modulators | HAVCR2, COPB1, HDLBP | NOTUM 4325/4885KDM4E 3751/4885ALDH1A1 3850/4885 |
| US-20220298110-A1 | HEPATITIS B CAPSID ASSEMBLY MODULATORS | HAVCR2, COPB1, HDLBP | NOTUM 4325/4885KDM4E 3751/4885ALDH1A1 3850/4885 |
| US-20210171439-A1 | HEPATITIS B CAPSID ASSEMBLY MODULATORS | HAVCR2, COPB1, HDLBP | NOTUM 4325/4885KDM4E 3751/4885ALDH1A1 3850/4885 |
| US-11247965-B2 | Hepatitis B capsid assembly modulators | HAVCR2, COPB1, HDLBP | NOTUM 4325/4885KDM4E 3751/4885ALDH1A1 3850/4885 |
| US-20040106521-A1 | Plant safening agents; | CBR3, CBR1, CYCS | NOTUM 1808/4885KDM4E 3053/4885ALDH1A1 2553/4885 |
| US-11014881-B2 | Hepatitis B capsid assembly modulators | HAVCR2, COPB1, HDLBP | NOTUM 4325/4885KDM4E 3751/4885ALDH1A1 3850/4885 |
| US-20090163488-A1 | FUSED HETEROCYCLE DERIVATIVES AND USE THEREOF | NOX3, NOX5, ZYX | NOTUM 2881/4885KDM4E 2148/4885ALDH1A1 2812/4885 |
| US-20040049035-A1 | Pyrrolecarboxamides and pyrrolethioamides as fungicides | CBR3, CBR1, PPOX | NOTUM 482/4885KDM4E 877/4885ALDH1A1 3025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.