Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.73 |
| ▸ | LMNA | P02545 | 5/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | PGR | P06401 | 2/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.73 |
| ▸ | RAB9A | P51151 | 1/20 | 0.73 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.73 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nilutamide SCHEMBL29351021 | 0.85 | AR (1.00) | ARLMNASMN1; SMN2CYP3A4MEN1 | |
| Nilutamide SCHEMBL12670 | 0.85 | AR (1.00) | ARLMNASMN1; SMN2CYP3A4MEN1 | |
| Nilutamide SCHEMBL1462011 | 0.85 | AR (1.00) | ARLMNASMN1; SMN2CYP3A4MEN1 | |
| Nilutamide SCHEMBL28562851 | 0.84 | AR (0.98) | ARLMNASMN1; SMN2CYP3A4MEN1 | |
| Nilutamide SCHEMBL20695037 | 0.80 | AR (0.89) | ARLMNASMN1; SMN2CYP3A4MEN1 | |
| Nilutamide SCHEMBL5579273 | 0.80 | AR (0.89) | ARLMNASMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL8407306 | 0.78 | AR (0.78) | ARLMNASMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL4026041 | 0.77 | AR (0.70) | ARLMNASMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL9737180 | 0.75 | AR (0.52) | ARLMNASMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL4023707 | 0.75 | AR (0.73) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097996-A1 | USE OF SUBSTITUTED PHENYLIMIDAZOLIDINES FOR PRODUCING MEDICAMENTS FOR TREATING METABOLIC SYNDROME | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |