Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL634212 | 0.82 | AR (0.61) | ARKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4030854 | 0.75 | AR (0.73) | ARKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6141421 | 0.74 | HPN (0.49) | ARKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6140611 | 0.73 | POLB (0.56) | ARKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28901655 | 0.72 | SLC6A9 (0.48) | KMT2ACYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL993768 | 0.72 | HTT (0.64) | LMNASMN1; SMN2PDE7AALDH1A1L3MBTL1 | |
| SCHEMBL11266362 | 0.72 | CASP1 (0.42) | KMT2ACYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL993767 | 0.72 | HTT (0.64) | LMNASMN1; SMN2PDE7AALDH1A1L3MBTL1 | |
| SCHEMBL25259776 | 0.71 | PDE7A (0.44) | ARKMT2APDE7APOLBALDH1A1 | |
| SCHEMBL29378218 | 0.71 | GAA (0.61) | KMT2ACYP1A2CYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506763-A1 | SITE-SPECIFIC RECOMBINATION OF DNA IN PLANT CELLS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-07 | — | — | EP | disclosed |