Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.52 |
| ▸ | ABAT | P80404 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952649 | 0.83 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL4956384 | 0.83 | CYP2A6 (0.69) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL31171 | 0.83 | CYP2A6 (0.69) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| Water SCHEMBL29197442 | 0.79 | CYP2A6 (0.65) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| Hydrochloric Acid SCHEMBL28807787 | 0.79 | CYP2A6 (0.65) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| Formaldehyde SCHEMBL20477527 | 0.76 | CYP2A6 (0.61) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL1713358 | 0.75 | — | — | |
| SCHEMBL25288128 | 0.73 | CYP2A6 (0.58) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL9004502 | 0.73 | CYP2A6 (0.58) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL4195177 | 0.73 | CYP2A6 (0.58) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4631323-A | DOPING WITH CHARGE TRANSFER COMPOUNDS | HONEYWELL INC. (US) | 1986-12-23 | — | — | US | claimed |
| EP-4157458-B1 | TRIARYLPYRIDINE COMPOUNDS AND USE THEREOF FOR TREATING CANCER | INST NAT SANTE RECH MED (FR) | 2024-04-17 | — | — | EP | disclosed |
| CN-114716289-B | Preparation method of chiral benzyl alcohol derivative | 华中师范大学 | 2024-03-01 | — | — | CN | disclosed |
| US-20230212146-A1 | TRIARYLPYRIDINE COMPOUNDS AND USE THEREOF FOR TREATING CANCER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2023-07-06 | — | — | US | disclosed |
| CN-114716289-A | Preparation method of chiral benzyl alcohol derivative | 华中师范大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-111937892-A | Application of Aza-type isoalburnine derivative in prevention and treatment of agricultural plant diseases | 兰州大学 | 2020-11-17 | — | — | CN | disclosed |
| CN-111233706-A | Green synthesis method of sulindac | 安徽峆一药业股份有限公司 | 2020-06-05 | — | — | CN | disclosed |
| EP-1363635-B1 | SUBSTITUTED 8-ARYLQUINOLINE PHOSPHODIESTERASE-4 INHIBITORS | MERCK & CO INC (US) | 2009-04-15 | — | — | EP | disclosed |
| US-20090042888-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | BLACK LAWRENCE A | 2009-02-12 | — | — | US | disclosed |
| US-7427635-B2 | Substituted hydantoins | HOFFMANN-LA ROCHE INC. (US) | 2008-09-23 | — | — | US | disclosed |
| US-5691373-A | TREATING SUBARACHNOID HEMORRHAGE | WARNER-LAMBERT COMPANY (US) | 1997-11-25 | — | — | US | disclosed |
| EP-0772601-A1 | 4,5-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-05-14 | — | — | EP | disclosed |
| US-5620999-A | ANTIARTHRITIC, ANALGESIC AND ANTIPYRATIC AGENT | G.D. SEARLE & CO. | 1997-04-15 | — | — | US | disclosed |
| EP-0714391-A1 | SUBSTITUTED 2(5H)FURANONE, 2(5H)THIOPHENONE AND 2(5H)PYRROLONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ENDOTHELIN ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1996003387-A1 | 4,5-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-02-08 | — | — | WO | disclosed |
| EP-0624159-A4 | PYRIDYL SUBSTITUTED IMIDAZOLES. | SMITHKLINE BEECHAM CORP (US) | 1995-04-12 | — | — | EP | disclosed |
| WO-1995005376-A1 | SUBSTITUTED 2(5H)FURANONE, 2(5H)THIOPHENONE AND 2(5H)PYRROLONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ENDOTHELIN ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-02-23 | — | — | WO | disclosed |
| EP-0624159-A1 | PYRIDYL SUBSTITUTED IMIDAZOLES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-11-17 | — | — | EP | disclosed |
| WO-1993014082-A1 | PYRIDYL SUBSTITUTED IMIDAZOLES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-07-22 | — | — | WO | disclosed |
| EP-0433662-A2 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042888-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | PTGIS, PTGS1, PTGS2 | CYP2A6 90/4885HSD17B10 234/4885ALDH5A1 95/4885 |
| US-20230212146-A1 | TRIARYLPYRIDINE COMPOUNDS AND USE THEREOF FOR TREATING CANCER | TPX2, BRD4, BET1 | CYP2A6 2948/4885HSD17B10 4789/4885ALDH5A1 3232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.