SCHEMBL403133

SCHEMBL403133

Cc1ccc(N(c2ccc(C)cc2)c2cccc(C)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 0.48
HSD17B1 P14061 3/20 0.42
HSD17B2 P37059 3/20 0.42
ALDH1A1 P00352 4/20 0.42
TSHR P16473 3/20 0.42
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
TP53 P04637 1/20 0.41
GPX4 P36969 1/20 0.41
PAX8 Q06710 1/20 0.41
TDP1 Q9NUW8 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
NSD2 O96028 1/20 0.40
CASP3 P42574 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19075300 1.00 ACHE (0.48) ACHEHSD17B1HSD17B2ALDH1A1TSHR
SCHEMBL3441917 1.00 ACHE (0.48) ACHEHSD17B1HSD17B2ALDH1A1TSHR
SCHEMBL16158477 1.00 ACHE (0.48) ACHEHSD17B1HSD17B2ALDH1A1TSHR
SCHEMBL10066016 1.00 ACHE (0.48) ACHEHSD17B1HSD17B2ALDH1A1TSHR
SCHEMBL7741726 0.98 ACHE (0.46) ACHEHSD17B1HSD17B2ALDH1A1TSHR
SCHEMBL11331014 0.96 ACHE (0.46) ACHEHSD17B1HSD17B2ALDH1A1TSHR
SCHEMBL10065418 0.96 ACHE (0.46) ACHEHSD17B1HSD17B2ALDH1A1TSHR
SCHEMBL12957236 0.96 ACHE (0.46) ACHEHSD17B1HSD17B2ALDH1A1TSHR
SCHEMBL13764958 0.96 ACHE (0.46) ACHEHSD17B1HSD17B2ALDH1A1TSHR
SCHEMBL2611153 0.96 ACHE (0.46) ACHEHSD17B1HSD17B2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7267917-B2 Photoreceptor charge transport layer composition XEROX CORPORATION (US) 2007-09-11 US claimed
US-20060063080-A1 Photoreceptor charge transport layer composition XEROX CORPORATION (US) 2006-03-23 US claimed
EP-3257093-B1 ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS MERCK PATENT GMBH (DE) 2021-07-07 EP disclosed
EP-3112439-B1 LUMINESCENT MATERIAL, ORGANIC LUMINESCENT ELEMENT, AND COMPOUND KYULUX INC (JP) 2021-06-23 EP disclosed
US-20190221375-A1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, AND OXIDE SEMICONDUCTOR ELECTRODE FUJIFILM CORPORATION (JP) 2019-07-18 US disclosed
EP-3425689-A1 CHARGE-TRANSPORTING VARNISH Nissan Chemical Corporation (JP) 2019-01-09 EP disclosed
US-20180040832-A1 ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS MERCK PATENT GMBH (DE) 2018-02-08 US disclosed
US-20170365786-A1 COMPOSITIONS COMPRISING AT LEAST ONE POLYMER AND AT LEAST ONE METAL COMPLEX AND TO ELECTROLUMINESCENT DEVICES CONTAINING SAID COMPOSITIONS MERCK PATENT GMBH (DE) 2017-12-21 US disclosed
US-20170365785-A1 COMPOSITIONS COMPRISING AT LEAST ONE POLYMER AND AT LEAST ONE SALT, AND ELECTROLUMINESCENT DEVICES CONTAINING SAID COMPOSITIONS MERCK PATENT GMBH (DE) 2017-12-21 US disclosed
US-9815940-B2 Polymers containing substituted triarylamine units and electroluminescent devices containing said polymers MERCK PATENT GMBH (DE) 2017-11-14 US disclosed
US-9745420-B2 Polymers containing substituted oligo-triarylamine units and electroluminescence devices containing such polymers MERCK PATENT GMBH (DE) 2017-08-29 US disclosed
US-20070023747-A1 Positive charging photoreceptor XEROX CORPORATION (US) 2007-02-01 US disclosed
US-20060292466-A1 Photoreceptor with three-layer photoconductive layer XEROX CORPORATION (US) 2006-12-28 US disclosed
US-20060216620-A1 Photoconductive imaging member XEROX CORPORATION 2006-09-28 US disclosed
US-20060204872-A1 Hydrolyzed semi-conductive nanoparticles for imaging member undercoating layers XEROX CORPORATION (US) 2006-09-14 US disclosed
US-20060204873-A1 Electron conductive overcoat layer for photoreceptors XEROX CORPORATION (US) 2006-09-14 US disclosed
US-20060177748-A1 High-performance surface layer for photoreceptors XEROX CORPORATION (US) 2006-08-10 US disclosed
US-20060063080-A1 Photoreceptor charge transport layer composition XEROX CORPORATION (US) 2006-03-23 US disclosed
EP-0275567-B1 NOVEL ORGANIC COMPOUNDS FOR USE IN ELECTROPHOTOGRAPHIC ELEMENTS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1991-12-11 EP disclosed
US-4788336-A HEAT AND OXIDATION RESISTANCE EASTMAN KODAK COMPANY (US) 1988-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180040832-A1 ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS OXA1L, UROD, MRPL21 ACHE 83/4885HSD17B1 2019/4885HSD17B2 2121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.