SCHEMBL7741726

SCHEMBL7741726

Cc1ccc(N(c2cccc(C)c2)c2cccc(N(c3ccc(C)cc3)c3cccc(C)c3)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.46
HSD17B1 P14061 4/20 0.41
HSD17B2 P37059 4/20 0.41
ALDH1A1 P00352 5/20 0.41
TSHR P16473 3/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
TP53 P04637 1/20 0.40
GPX4 P36969 1/20 0.40
PAX8 Q06710 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
NSD2 O96028 1/20 0.39
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL403133 0.98 ACHE (0.48) ACHEHSD17B1HSD17B2ALDH1A1TSHR
SCHEMBL19075300 0.98 ACHE (0.48) ACHEHSD17B1HSD17B2ALDH1A1TSHR
SCHEMBL3441917 0.98 ACHE (0.48) ACHEHSD17B1HSD17B2ALDH1A1TSHR
SCHEMBL10066016 0.98 ACHE (0.48) ACHEHSD17B1HSD17B2ALDH1A1TSHR
SCHEMBL16158477 0.98 ACHE (0.48) ACHEHSD17B1HSD17B2ALDH1A1TSHR
SCHEMBL8764994 0.96 ACHE (0.42) ACHEHSD17B1HSD17B2ALDH1A1TSHR
SCHEMBL13764958 0.94 ACHE (0.46) ACHEHSD17B1HSD17B2ALDH1A1TSHR
SCHEMBL11331014 0.94 ACHE (0.46) ACHEHSD17B1HSD17B2ALDH1A1TSHR
SCHEMBL10065418 0.94 ACHE (0.46) ACHEHSD17B1HSD17B2ALDH1A1TSHR
SCHEMBL12957236 0.94 ACHE (0.46) ACHEHSD17B1HSD17B2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0390195-B1 Electrophotosensitive material MITA INDUSTRIAL CO LTD (JP) 1994-03-02 EP claimed
JP-2258747-A None JP disclosed
US-6409812-B1 MONOAZO DYE; PAINTS, INK JETS, COLOR FILTERS; ELECTROGRAPHY; DIAZOTIZATION KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2002-06-25 US disclosed
EP-0420207-B1 Electrophotosensitive material and method of manufacturing the same MITA INDUSTRIAL CO LTD (JP) 1997-08-13 EP disclosed
EP-0466406-B1 An electrophotographic photoconductor and a method for preparing the same MITA INDUSTRIAL CO LTD (JP) 1997-06-11 EP disclosed
EP-0390196-B1 Electrophotosensitive material MITA INDUSTRIAL CO LTD (JP) 1995-09-20 EP disclosed
US-5374772-A Skin disorders, antiinflammatory agents, cardiovascular disorders HOFFMANN-LAROCHE INC. (US) 1994-12-20 US disclosed
EP-0601385-A1 Disubstituted benzoic acid derivatives F. HOFFMANN-LA ROCHE AG (CH) 1994-06-15 EP disclosed
EP-0390195-B1 Electrophotosensitive material MITA INDUSTRIAL CO LTD (JP) 1994-03-02 EP disclosed
US-5223364-A Having perylene pigment as charge generating compound MITA INDUSTRIAL CO., LTD. (JP) 1993-06-29 US disclosed
US-5185228-A Binder resin, charge transfer material; stability MITA INDUSTRIAL CO., LTD. (JP) 1993-02-09 US disclosed
US-5128229-A Polycarbonate, m-phenylenediamine derivative MITA INDUSTRIAL CO., LTD. (JP) 1992-07-07 US disclosed
EP-0466406-A1 An electrophotographic photoconductor and a method for preparing the same MITA INDUSTRIAL CO., LTD. (JP) 1992-01-15 EP disclosed
US-5059503-A Used for copying machine MITA INDUSTRIAL CO., LTD. (JP) 1991-10-22 US disclosed
EP-0420207-A2 Electrophotosensitive material and method of manufacturing the same MITA INDUSTRIAL CO. LTD. (JP) 1991-04-03 EP disclosed
EP-0413338-A1 Electrophotosensitive material MITA INDUSTRIAL CO. LTD. (JP) 1991-02-20 EP disclosed
JP-H02258747-A 1,3-PHENYLENEDIAMINE DERIVATIVE AND PRODUCTION THEREOF NIPPON JIYOURIYUU KOGYO KK 1990-10-19 JP disclosed
EP-0390196-A2 Electrophotosensitive material MITA INDUSTRIAL CO., LTD. (JP) 1990-10-03 EP disclosed