Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13503924 | 0.75 | ALDH1A1 (0.69) | SLC6A2SLC6A4SLC6A3HRH3KMT2A | |
| SCHEMBL4013523 | 0.74 | HRH3 (0.68) | SLC6A2SLC6A4SLC6A3HRH3ALDH1A1 | |
| SCHEMBL20812317 | 0.72 | ACACB (0.54) | SLC6A2SLC6A4SLC6A3HRH3KMT2A | |
| SCHEMBL4374335 | 0.70 | HRH3 (0.33) | SLC6A2SLC6A4SLC6A3HRH3NPSR1 | |
| SCHEMBL20805385 | 0.70 | HRH3 (0.52) | SLC6A2SLC6A4SLC6A3HRH3KMT2A | |
| SCHEMBL19605006 | 0.69 | HRH3 (0.59) | HRH3KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19464759 | 0.69 | ALDH1A1 (0.57) | SLC6A2SLC6A4SLC6A3HRH3KMT2A | |
| SCHEMBL23102110 | 0.68 | HRH3 (0.55) | HRH3KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28759342 | 0.65 | CRBN (0.53) | KMT2AMEN1ALDH1A1PKMKDM4E | |
| SCHEMBL13503762 | 0.65 | EPHX2 (0.61) | HRH3KMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049473-A2 | SUBSTITUTED BENZYL AMINE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008002820-A2 | SUBSTITUTED BENZYL AMINE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-01-03 | — | — | WO | disclosed |