Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898794 | 0.88 | MEN1 (0.55) | CRBNMEN1KMT2AEPHX2CNR2 | |
| SCHEMBL5510365 | 0.86 | CRBN (0.52) | CRBNMEN1KMT2AEPHX2CNR2 | |
| SCHEMBL10069581 | 0.83 | ALDH1A1 (0.70) | CRBNMEN1KMT2AEPHX2CNR2 | |
| SCHEMBL16855800 | 0.82 | GLS (0.53) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL31709335 | 0.82 | GPR119 (0.56) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2195878 | 0.82 | MEN1 (0.56) | CRBNMEN1KMT2AEPHX2CNR2 | |
| SCHEMBL15764549 | 0.82 | MEN1 (0.56) | CRBNMEN1KMT2AEPHX2CNR2 | |
| SCHEMBL3731690 | 0.82 | EPHX2 (0.57) | CRBNMEN1KMT2AEPHX2CNR2 | |
| SCHEMBL15986829 | 0.81 | CRBN (0.55) | CRBNMEN1KMT2AEPHX2CNR2 | |
| SCHEMBL221577 | 0.81 | LMNA (0.70) | CRBNMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114599428-A | Bifunctional compounds | 豪夫迈·罗氏有限公司 | 2022-06-07 | — | — | CN | disclosed |