Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methoxyphenamine SCHEMBL29390678 | 0.83 | TAAR1 (0.50) | IDO1CYP2D6GAAALDH1A1CYP3A4 | |
| Methoxyphenamine SCHEMBL218289 | 0.83 | TAAR1 (0.50) | IDO1CYP2D6GAAALDH1A1CYP3A4 | |
| Methoxyphenamine SCHEMBL2751759 | 0.83 | TAAR1 (0.50) | IDO1CYP2D6GAAALDH1A1CYP3A4 | |
| SCHEMBL14113381 | 0.83 | GABRA1 (0.68) | IDO1CALM1ALOX5PTGS2CYP2D6 | |
| Methoxyphenamine SCHEMBL14655868 | 0.83 | TAAR1 (0.50) | IDO1CYP2D6GAAALDH1A1CYP3A4 | |
| SCHEMBL20545745 | 0.82 | ALDH1A1 (0.53) | CYP2D6CYP2C19GAAALDH1A1KDM4E | |
| Methoxyphenamine SCHEMBL208636 | 0.81 | ALDH1A1 (0.51) | IDO1CYP2D6CYP2C19GAAALDH1A1 | |
| Methoxyphenamine SCHEMBL29379229 | 0.81 | ALDH1A1 (0.51) | IDO1CYP2D6CYP2C19GAAALDH1A1 | |
| SCHEMBL20668124 | 0.80 | IDO1 (0.54) | IDO1CALM1ALOX5PTGS2CYP2D6 | |
| SCHEMBL16670389 | 0.80 | IDO1 (0.54) | IDO1CALM1ALOX5PTGS2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701948-A4 | ASSAY FOR ENTACTOGENS | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2009-03-04 | — | — | EP | disclosed |
| EP-1701948-A1 | ASSAY FOR ENTACTOGENS | DADE BEHRING INC. (US) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005058864-A1 | ASSAY FOR ENTACTOGENS | DADE BEHRING INC. (US) | 2005-06-30 | — | — | WO | disclosed |