Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.37 |
| ▸ | CTSA | P10619 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4037529 | 0.91 | CTSA (0.37) | MEN1KMT2AGPBAR1LPAR1LPAR2 | |
| SCHEMBL4028274 | 0.88 | LPAR1 (0.37) | MEN1KMT2AGPBAR1LPAR1LPAR2 | |
| SCHEMBL4034108 | 0.86 | LPAR1 (0.44) | MEN1KMT2ALPAR1LPAR2LPAR3 | |
| SCHEMBL4030969 | 0.86 | LPAR1 (0.38) | MEN1KMT2AGPBAR1LPAR1LPAR3 | |
| SCHEMBL4032476 | 0.85 | LPAR1 (0.43) | MEN1KMT2AGPBAR1LPAR1LPAR2 | |
| SCHEMBL15437656 | 0.84 | SCN9A (0.37) | MEN1KMT2ALPAR1LPAR2LPAR3 | |
| SCHEMBL15437515 | 0.84 | SCN9A (0.37) | MEN1KMT2ALPAR1LPAR2LPAR3 | |
| SCHEMBL4030964 | 0.84 | HDAC3 (0.39) | MEN1KMT2AGPBAR1LPAR1LPAR2 | |
| SCHEMBL4032656 | 0.83 | MEN1 (0.48) | MEN1KMT2AGPBAR1ALDH1A1GAA | |
| SCHEMBL4034159 | 0.83 | LPAR1 (0.44) | MEN1KMT2AGPBAR1LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1258484-B1 | NOVEL ISOXAZOLE AND THIAZOLE COMPOUNDS AND USE THEREOF AS DRUGS | KYOWA HAKKO KIRIN CO LTD (JP) | 2009-01-14 | — | — | EP | claimed |