Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | BLVRB | P30043 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032080 | 0.86 | MEN1 (0.40) | LPAR1LPAR3MEN1KMT2AALDH1A1 | |
| SCHEMBL4033561 | 0.84 | LPAR1 (0.42) | LPAR1LPAR3NPC1MEN1KMT2A | |
| SCHEMBL4028121 | 0.81 | LPAR1 (0.44) | LPAR1LPAR3POLBNPC1RAB9A | |
| SCHEMBL4034077 | 0.81 | HDAC3 (0.41) | LPAR1LPAR3MEN1KMT2AHDAC6 | |
| SCHEMBL4031584 | 0.80 | LPAR1 (0.43) | LPAR1LPAR3MEN1KMT2ASTAT3 | |
| SCHEMBL4027903 | 0.78 | HTT (0.45) | LPAR1LPAR3RAB9ASTAT3ALDH1A1 | |
| SCHEMBL4037529 | 0.77 | CTSA (0.37) | LPAR1LPAR3MEN1KMT2AALDH1A1 | |
| SCHEMBL4031919 | 0.76 | TRPA1 (0.50) | LPAR1LPAR3STAT3ALDH1A1PKM | |
| SCHEMBL4034111 | 0.76 | BRD4 (0.37) | LPAR1LPAR3POLBNPC1RAB9A | |
| SCHEMBL4030691 | 0.76 | LPAR1 (0.41) | LPAR1LPAR3NPSR1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1258484-B1 | NOVEL ISOXAZOLE AND THIAZOLE COMPOUNDS AND USE THEREOF AS DRUGS | KYOWA HAKKO KIRIN CO LTD (JP) | 2009-01-14 | — | — | EP | claimed |