Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032080 | 0.91 | MEN1 (0.40) | CTSAMEN1KMT2ALPAR1LPAR2 | |
| SCHEMBL4032476 | 0.87 | LPAR1 (0.43) | CTSAMEN1KMT2ALPAR1LPAR2 | |
| SCHEMBL15437515 | 0.87 | SCN9A (0.37) | MEN1KMT2ALPAR1LPAR2LPAR3 | |
| SCHEMBL15437656 | 0.87 | SCN9A (0.37) | MEN1KMT2ALPAR1LPAR2LPAR3 | |
| SCHEMBL4030964 | 0.85 | HDAC3 (0.39) | CTSAMEN1KMT2ALPAR1LPAR2 | |
| SCHEMBL4034108 | 0.83 | LPAR1 (0.44) | MEN1KMT2ALPAR1LPAR2LPAR3 | |
| SCHEMBL4028274 | 0.83 | LPAR1 (0.37) | MEN1KMT2ALPAR1LPAR2LPAR3 | |
| SCHEMBL4034159 | 0.81 | LPAR1 (0.44) | CTSAMEN1KMT2ALPAR1LPAR2 | |
| SCHEMBL4035057 | 0.80 | TP53 (0.41) | CTSAMEN1KMT2ALPAR1LPAR2 | |
| SCHEMBL4035115 | 0.80 | IP6K1 (0.40) | CTSALPAR1LPAR2LPAR3GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1258484-B1 | NOVEL ISOXAZOLE AND THIAZOLE COMPOUNDS AND USE THEREOF AS DRUGS | KYOWA HAKKO KIRIN CO LTD (JP) | 2009-01-14 | — | — | EP | claimed |