SCHEMBL4032294

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4032728	0.90	HRH3 (0.53)	HRH3ACKR3
	SCHEMBL4031748	0.87	HRH3 (0.53)	HRH3ACKR3
	SCHEMBL4032242	0.84	HRH3 (0.55)	HRH3
	SCHEMBL4032437	0.82	KMT2A (0.48)	HRH3KDM4EALDH1A1MAPTPKM
	SCHEMBL4035015	0.82	HRH3 (0.53)	HRH3KCNJ1ALDH1A1MAPT
	SCHEMBL4031972	0.77	HRH3 (0.65)	HRH3
	SCHEMBL5210405	0.77	HRH3 (0.61)	HRH3
	SCHEMBL4031793	0.77	HRH3 (0.42)	HRH3
	SCHEMBL4036526	0.76	HRH3 (0.54)	HRH3
	SCHEMBL5210165	0.74	HRH3 (0.59)	HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.