Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11589528 | 0.90 | PTGS2 (0.55) | PTGS2PPARGPPARATHRATHRB | |
| SCHEMBL1788428 | 0.89 | PPARG (0.62) | PTGS2PPARGPPARATHRATHRB | |
| SCHEMBL3873794 | 0.88 | PPARA (0.69) | PTGS2PPARGPPARATHRATHRB | |
| SCHEMBL7065312 | 0.87 | THRA (0.53) | PPARGPPARATHRATHRBPPARD | |
| SCHEMBL729676 | 0.87 | THRA (0.53) | PPARGPPARATHRATHRBPPARD | |
| SCHEMBL29581614 | 0.87 | THRA (0.53) | PPARGPPARATHRATHRBPPARD | |
| SCHEMBL16065424 | 0.87 | PPARG (0.59) | PTGS2PPARGPPARATHRATHRB | |
| SCHEMBL30850062 | 0.86 | PTGS2 (0.55) | PTGS2PPARGPPARAKDM4EALDH1A1 | |
| SCHEMBL68677 | 0.86 | PTGS2 (0.55) | PTGS2PPARGPPARAKDM4EALDH1A1 | |
| SCHEMBL7637671 | 0.86 | PPARA (0.72) | PTGS2PPARGPPARATHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102660393-B | Cleaning solution for light-emitting diode (LED) chip | CHANGSHU AOSHOU PHOTOELECTRIC MATERIALS CO LTD | 2013-07-24 | — | — | CN | claimed |
| CN-102660393-A | Cleaning solution for light-emitting diode (LED) chip | CHANGSHU AOSHOU PHOTOELECTRIC MATERIALS CO LTD | 2012-09-12 | — | — | CN | claimed |
| US-20240239934-A1 | FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE | TOSOH CORPORATION (JP) | 2024-07-18 | — | — | US | disclosed |
| US-20240239934-A1 | FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE | TOSOH CORPORATION (JP) | 2024-07-18 | — | — | US | disclosed |
| EP-4034520-A1 | LIGHT INDUCED CATALYTIC C-H OXYGENATION OF ALKANES | Ariel Scientific Innovations Ltd. (IL) | 2022-08-03 | — | — | EP | disclosed |
| WO-2021059287-A1 | LIGHT INDUCED CATALYTIC C-H OXYGENATION OF ALKANES | Ariel Scientific Innovations Ltd. (IL) | 2021-04-01 | — | — | WO | disclosed |
| US-9622993-B2 | Thiosemicarbazones inhibitors of lysophosphatidic acid acyltransferase and uses thereof | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2017-04-18 | — | — | US | disclosed |
| US-9622993-B2 | Thiosemicarbazones inhibitors of lysophosphatidic acid acyltransferase and uses thereof | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2017-04-18 | — | — | US | disclosed |
| US-20170027893-A1 | THIOSEMICARBAZONES INHIBITORS OF LYSOPHOSPHATIDIC ACID ACYLTRANSFERASE AND USES THEREOF | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2017-02-02 | — | — | US | disclosed |
| US-20170027893-A1 | THIOSEMICARBAZONES INHIBITORS OF LYSOPHOSPHATIDIC ACID ACYLTRANSFERASE AND USES THEREOF | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2017-02-02 | — | — | US | disclosed |
| WO-2015157242-A1 | THIOSEMICARBAZONES INHIBITORS OF LYSOPHOSPHATIDIC ACID ACYLTRANSFERASE AND USES THEREOF | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2015-10-15 | — | — | WO | disclosed |
| EP-1379240-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2009-04-08 | — | — | EP | disclosed |
| EP-1379240-A1 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002078696-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-10-10 | — | — | WO | disclosed |
| US-5684162-A | BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1997-11-04 | — | — | US | disclosed |
| EP-0787116-A1 | PROCESS FOR SEPARATING ENANTIOMERS FROM A RACEMIC MIXTURE | Akzo Nobel N.V. (NL) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996011894-A1 | PROCESS FOR SEPARATING ENANTIOMERS FROM A RACEMIC MIXTURE | AKZO NOBEL N.V. (NL) | 1996-04-25 | — | — | WO | disclosed |
| EP-0136195-A1 | Microbicidal benzamidine derivatives, their preparation and their use in pharmaceutical compositions as disinfection or preservation agents | SANOFI (FR) | 1985-04-03 | — | — | EP | disclosed |
| EP-0021636-A1 | Secondary amines, their preparation and use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-01-07 | — | — | EP | disclosed |
| US-4234733-A | PHENOL, ALIPHATIC ESTER OR ETHER, CARBON MONOXIDE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1980-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170027893-A1 | THIOSEMICARBAZONES INHIBITORS OF LYSOPHOSPHATIDIC ACID ACYLTRANSFERASE AND USES THEREOF | BRAF, PLAAT3, PLAAT2 | PTGS2 2190/4885PPARG 1504/4885PPARA 1345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.