Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4038173 | 0.89 | KMT2A (0.49) | KMT2AMAPTMEN1ALDH1A1CHRM4 | |
| SCHEMBL4034760 | 0.86 | KMT2A (0.51) | KMT2AMAPTMEN1ALDH1A1CHRM4 | |
| SCHEMBL5210554 | 0.86 | GPR119 (0.47) | KMT2AMAPTMEN1ALDH1A1GPR119 | |
| SCHEMBL4032425 | 0.85 | HRH1 (0.48) | KMT2AMAPTMEN1ALDH1A1CHRM4 | |
| SCHEMBL11736036 | 0.84 | DRD2 (0.60) | KMT2AMAPTMEN1ALDH1A1MAPK1 | |
| SCHEMBL24725739 | 0.82 | KMT2A (0.53) | KMT2AMAPTMEN1ALDH1A1CHRM4 | |
| SCHEMBL4032437 | 0.80 | KMT2A (0.48) | KMT2AMAPTMEN1ALDH1A1CHRM4 | |
| SCHEMBL4032905 | 0.79 | KMT2A (0.57) | KMT2AMAPTMEN1ALDH1A1GPR119 | |
| SCHEMBL30582718 | 0.77 | KMT2A (0.53) | KMT2AMAPTMEN1ALDH1A1CHRM4 | |
| SCHEMBL3770035 | 0.76 | USP2 (0.53) | KMT2AMAPTMEN1ALDH1A1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789410-B1 | METHYLENE DIPIPERIDINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2009-06-17 | — | — | EP | claimed |