Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.81 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.81 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.69 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.69 |
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.53 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27090233 | 0.92 | ESR1 (0.96) | ESR1ESR2PIK3CAPIK3CBAPP | |
| SCHEMBL4476460 | 0.90 | ESR1 (1.00) | ESR1ESR2PIK3CAPIK3CBAPP | |
| SCHEMBL9114641 | 0.87 | ESR1 (0.81) | ESR1ESR2PIK3CAPIK3CBAPP | |
| SCHEMBL13254495 | 0.86 | KDM4E (0.59) | ESR1ESR2PIK3CBMAPTHSPD1 | |
| SCHEMBL18726303 | 0.84 | ESR1 (0.81) | ESR1ESR2PIK3CAPIK3CBAPP | |
| SCHEMBL5901662 | 0.83 | ESR1 (0.81) | ESR1ESR2PIK3CAPIK3CBAPP | |
| SCHEMBL1375808 | 0.83 | ESR2 (1.00) | ESR1ESR2PIK3CAPIK3CBAPP | |
| SCHEMBL9467880 | 0.83 | HDAC6 (0.57) | ESR1ESR2MAPTHSPD1PTPN2 | |
| SCHEMBL16901786 | 0.83 | ESR1 (0.79) | ESR1ESR2PIK3CAPIK3CBAPP | |
| SCHEMBL4077794 | 0.82 | ESR1 (1.00) | ESR1ESR2PIK3CAPIK3CBAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3307798-B2 | ALIGNMENT COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2024-06-05 | — | — | EP | disclosed |
| CN-107743594-B | Alignment polymers | 光学转变公司 | 2022-07-01 | — | — | CN | disclosed |
| EP-3307797-B1 | ALIGNMENT POLYMERS | TRANSITIONS OPTICAL INC (US) | 2021-10-20 | — | — | EP | disclosed |
| US-11130912-B2 | Alignment polymers | TRANSITIONS OPTICAL, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-10875833-B2 | Alignment compounds | TRANSITIONS OPTICAL, INC. (US) | 2020-12-29 | — | — | US | disclosed |
| EP-3307798-B1 | ALIGNMENT COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2020-08-05 | — | — | EP | disclosed |
| US-20180127653-A1 | Alignment Polymers | TRANSITIONS OPTICAL, INC. | 2018-05-10 | — | — | US | disclosed |
| US-20180086725-A1 | Alignment Compounds | TRANSITIONS OPTICAL, INC. | 2018-03-29 | — | — | US | disclosed |
| EP-1806346-B1 | Substituted piperazine compounds and their use as fatty acid oxidation inhibitors | CV THERAPEUTICS INC (US) | 2009-07-22 | — | — | EP | disclosed |
| US-7407960-B2 | Substituted heterocyclic compounds | CV THERAPEUTICS, INC. (US) | 2008-08-05 | — | — | US | disclosed |
| US-7125876-B2 | Substituted heterocyclic compounds | CV THERAPEUTICS, INC. (US) | 2006-10-24 | — | — | US | disclosed |
| EP-1567525-A2 | SUBSTITUTED PIPERAZINE COMPOUNDS AND THEIR USE AS FATTY ACID OXIDATION INHIBITORS | CV THERAPEUTICS, INC. (US) | 2005-08-31 | — | — | EP | disclosed |
| US-20040152890-A1 | Substituted heterocyclic compounds | CV THERAPEUTICS, INC. | 2004-08-05 | — | — | US | disclosed |
| WO-2004052887-A2 | SUBSTITUTED PIPERAZINE COMPOUNDS AND THEIR USE AS FATTY ACID OXIDATION INHIBITORS | CV THERAPEUTICS, INC. (US) | 2004-06-24 | — | — | WO | disclosed |
| EP-0623115-A4 | NUCLEOPHILIC DISPLACEMENT METHOD FOR SYNTHESIS OF NON-RIGID PBZ POLYMERS. | DOW CHEMICAL CO (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0623115-A1 | NUCLEOPHILIC DISPLACEMENT METHOD FOR SYNTHESIS OF NON-RIGID PBZ POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014071-A1 | NUCLEOPHILIC DISPLACEMENT METHOD FOR SYNTHESIS OF NON-RIGID PBZ POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1993-07-22 | — | — | WO | disclosed |
| US-5216110-A | Monomers useful in nucleophilic displacement synthesis of polybenzazole polymers | THE DOW CHEMICAL COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| US-5194562-A | Nucleophilic displacement method for synthesis of non-rigid PBZ polymers | THE DOW CHEMICAL COMPANY (US) | 1993-03-16 | — | — | US | disclosed |
| US-5104960-A | Nucleophilic displacement method for synthesis of non-rigid PBZ polymers | THE DOW CHEMICAL COMPANY (US) | 1992-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10875833-B2 | Alignment compounds | CYP19A1, ESR1, CCNE2 | ESR1 2/4885ESR2 44/4885PIK3CA 866/4885 |
| US-20040152890-A1 | Substituted heterocyclic compounds | KCNH1, SDHA, COQ8A | ESR1 3761/4885ESR2 2283/4885PIK3CA 1912/4885 |
| US-20180086725-A1 | Alignment Compounds | CYP19A1, ESR1, CCNE2 | ESR1 2/4885ESR2 44/4885PIK3CA 866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.