Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TTR | P02766 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.60 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.60 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.60 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035625 | 0.95 | LTB4R (0.61) | PPARATDP1SMN1; SMN2TTRCYP1A2 | |
| SCHEMBL3484594 | 0.87 | LMNA (0.48) | PPARATDP1SMN1; SMN2TTRCYP1A2 | |
| SCHEMBL4035649 | 0.86 | PPARA (0.49) | PPARATDP1SMN1; SMN2TTRCYP1A2 | |
| SCHEMBL11097988 | 0.84 | PPARA (0.60) | PPARATDP1SMN1; SMN2TTRCYP1A2 | |
| SCHEMBL3484528 | 0.83 | LTB4R (0.48) | TDP1SMN1; SMN2LTB4RLMNAL3MBTL1 | |
| SCHEMBL4034269 | 0.82 | LTB4R (0.48) | PPARALTB4RKDM4EALDH1A1 | |
| SCHEMBL4036598 | 0.79 | PPARA (0.77) | PPARATDP1SMN1; SMN2TTRCYP1A2 | |
| SCHEMBL12958327 | 0.79 | SYK (0.52) | TDP1SMN1; SMN2LMNAL3MBTL1MAPK1 | |
| SCHEMBL11096802 | 0.79 | PPARA (0.62) | PPARATDP1SMN1; SMN2TTRCYP1A2 | |
| SCHEMBL11090691 | 0.78 | PPARA (0.61) | PPARATDP1SMN1; SMN2TTRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049107-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | Genfit (FR) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |