SCHEMBL10137650

SCHEMBL10137650

CC(C)(C)OC(=O)N[C@@H]1CCCC[C@H]1C(=O)OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CPB1 P15086 2/20 0.56
CTSL P07711 2/20 0.50
CTSB P07858 2/20 0.50
CTSS P25774 2/20 0.50
CTSK P43235 2/20 0.50
CASP3 P42574 3/20 0.49
KMT2A Q03164 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
PDE4B Q07343 1/20 0.49
FKBP1A P62942 3/20 0.46
SYK P43405 1/20 0.45
ALDH1A1 P00352 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12873056 1.00 CPB1 (0.56) CPB1CTSLCTSBCTSSCTSK
SCHEMBL24515752 0.98 CPB1 (0.56) CPB1CTSLCTSBCTSSCTSK
SCHEMBL24515749 0.98 CPB1 (0.56) CPB1CTSLCTSBCTSSCTSK
SCHEMBL4033681 0.88 CPB1 (0.54) CPB1CTSLCTSBCTSSCTSK
SCHEMBL3563686 0.85 KMT2A (0.56) CPB1CTSLCTSBCTSSCTSK
SCHEMBL2496331 0.85 CACNA1B (0.51) CPB1CTSBCTSSCTSKKMT2A
SCHEMBL15096069 0.84 CPB1 (0.50) CPB1CTSLCTSBCTSSCTSK
SCHEMBL8296191 0.83 CPB1 (0.64) CPB1CTSLCTSBCTSSCTSK
SCHEMBL28854927 0.83 CPB1 (0.64) CPB1CTSLCTSBCTSSCTSK
SCHEMBL10303639 0.83 CPB1 (0.78) CPB1CTSLCTSBCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10322998-B2 Heterogeneous foldamers containing α, β, and/or γ-amino acids WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2019-06-18 US disclosed
US-20120021530-A1 HETEROGENEOUS FOLDAMERS CONTAINING alpha, beta, and/or gamma-AMINO ACIDS WISCONSIN ALUMNI RESEARCH FOUNDATION 2012-01-26 US disclosed
US-7858737-B2 Heterogeneous foldamers containing α, β, and/or γ-amino acids WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2010-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10322998-B2 Heterogeneous foldamers containing α, β, and/or γ-amino acids DNPEP, PRKCSH, BCAT1 CPB1 85/4885CTSL 2168/4885CTSB 1157/4885
US-20120021530-A1 HETEROGENEOUS FOLDAMERS CONTAINING alpha, beta, and/or gamma-AMINO ACIDS DNPEP, PRKCSH, YWHAZ CPB1 118/4885CTSL 2183/4885CTSB 1184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.