SCHEMBL4033783

SCHEMBL4033783

c1ccc(Cc2cccc3ncc4ccccc4c23)cc1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.49
GPR3 P46089 1/20 0.49
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
ELANE P08246 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
MET P08581 1/20 0.38
PAX8 Q06710 1/20 0.37
PDE5A O76074 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9935648 0.82 KDM4E (0.53) KDM4EGPR3KMT2ACYP1A2CYP2C9
SCHEMBL9935646 0.82 KDM4E (0.53) KDM4EGPR3KMT2AMEN1CYP1A2
SCHEMBL27279082 0.81 KDM4E (0.52) KDM4EGPR3KMT2ACYP1A2CYP2C9
SCHEMBL5801178 0.81 KDM4E (0.52) KDM4EGPR3KMT2AMEN1ELANE
SCHEMBL28355479 0.81 KDM4E (0.52) KDM4EGPR3KMT2AMEN1ELANE
SCHEMBL27588351 0.81 KDM4E (0.52) KDM4EGPR3KMT2ACYP1A2CYP2C9
SCHEMBL1860385 0.78 KDM4E (0.49) KDM4EGPR3KMT2AMEN1CYP1A2
SCHEMBL10976790 0.78 KDM4E (0.49) KDM4EGPR3ELANECYP1A2
SCHEMBL28328727 0.78 KDM4E (0.49) KDM4EGPR3KMT2AMEN1L3MBTL1
SCHEMBL1505063 0.77 KDM4E (0.47) KDM4EGPR3KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111954706-B Polymerizable liquid crystal compound, liquid crystal composition for optical element, polymer, optically anisotropic body, and optical element for display device 株式会社LG化学 2023-09-08 CN disclosed
US-11365354-B2 Polymerizable liquid crystal compound, liquid crystal composition for optical element, polymer, optically anisotropic body, and optical element for display device LG CHEM, LTD. 2022-06-21 US disclosed
US-11085060-B2 Pterin-dependent biocatalysts and uses thereof GEORGIA TECH RESEARCH CORPORATION (US) 2021-08-10 US disclosed
EP-3789471-B1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION FOR OPTICAL ELEMENT, POLYMER, OPTICALLY ANISOTROPIC BODY, AND OPTICAL ELEMENT FOR DISPLAY DEVICE LG CHEMICAL LTD (KR) 2021-06-09 EP disclosed
US-20210155852-A1 Polymerizable Liquid Crystal Compound, Liquid Crystal Composition for Optical Element, Polymer, Optically Anisotropic Body, and Optical Element for Display Device LG CHEM, LTD. (KR) 2021-05-27 US disclosed
EP-3789471-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION FOR OPTICAL ELEMENT, POLYMER, OPTICALLY ANISOTROPIC BODY, AND OPTICAL ELEMENT FOR DISPLAY DEVICE LG CHEM, LTD. (KR) 2021-03-10 EP disclosed
CN-111954706-A Polymerizable liquid crystal compound, liquid crystal composition for optical element, polymer, optically anisotropic body, and optical element for display device 株式会社LG化学 2020-11-17 CN disclosed
US-20170362617-A1 PTERIN-DEPENDENT BIOCATALYSTS AND USES THEREOF GEORGIA TECH RESEARCH CORPORATION 2017-12-21 US disclosed
CN-107235900-A The synthetic method of 6 benzyl phenanthridines class compounds 温州大学 2017-10-10 CN disclosed
CN-107235900-A The synthetic method of 6 benzyl phenanthridines class compounds 温州大学 2017-10-10 CN disclosed
WO-2016109769-A1 PTERIN-DEPENDENT BIOCATALYSTS AND USES THEREOF GEORGIA TECH RESEARCH CORPORATION (US) 2016-07-07 WO disclosed
US-7531008-B2 Use of at least one cationic cyanin derivative for dyeing the hair, composition containing it, process for treating keratin fibers using the composition, and device therefor L'OREAL S.A. (FR) 2009-05-12 US disclosed
US-20070143936-A1 Use of at least one cationic cyanin derivative for dyeing the hair, composition containing it, process for treating keratin fibers using the composition, and device therefor L'OREAL S.A. (FR) 2007-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070143936-A1 Use of at least one cationic cyanin derivative for dyeing the hair, composition containing it, process for treating keratin fibers using the composition, and device therefor KRT18, HKDC1, DSC1 KDM4E 1561/4885GPR3 4225/4885CYP11B1 1197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.