Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GPR3 | P46089 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | PKM | P14618 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27588351 | 0.83 | KDM4E (0.52) | KDM4EGPR3MAPTKMT2AHTT | |
| SCHEMBL9935646 | 0.81 | KDM4E (0.53) | KDM4EGPR3MAPTMEN1KMT2A | |
| SCHEMBL9935648 | 0.81 | KDM4E (0.53) | KDM4EGPR3KMT2AHTTALDH1A1 | |
| SCHEMBL5801178 | 0.80 | KDM4E (0.52) | KDM4EGPR3MAPTMEN1KMT2A | |
| SCHEMBL28355479 | 0.80 | KDM4E (0.52) | KDM4EGPR3MAPTMEN1KMT2A | |
| SCHEMBL27279082 | 0.80 | KDM4E (0.52) | KDM4EGPR3KMT2AHTTALDH1A1 | |
| SCHEMBL27670163 | 0.79 | CYP3A4 (0.45) | KDM4EMAPTALDH1A1LMNAHIF1A | |
| SCHEMBL16487070 | 0.77 | ALDH1A1 (0.43) | KDM4EGABRA1GABRB2MAPTMEN1 | |
| SCHEMBL1860385 | 0.77 | KDM4E (0.49) | KDM4EGPR3MAPTMEN1KMT2A | |
| SCHEMBL4033783 | 0.77 | KDM4E (0.49) | KDM4EGPR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103936661-B | A kind of synthetic method of 6-alkyl phenanthrene piperidine derivatives | 常州大学 | 2016-08-24 | — | — | CN | claimed |
| CN-115724797-A | Fluoroalkylated 3, 4-polysubstituted dihydroisoquinoline skeleton novel compound and preparation method thereof | 兰州大学 | 2023-03-03 | — | — | CN | disclosed |
| CN-108299297-A | A kind of novel 6- alkyl phenanthridines and derivative and preparation method thereof | 西京学院 | 2018-07-20 | — | — | CN | disclosed |
| CN-103936661-B | A kind of synthetic method of 6-alkyl phenanthrene piperidine derivatives | 常州大学 | 2016-08-24 | — | — | CN | disclosed |
| US-20120313089-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | UDC IRELAND LTD. (IE) | 2012-12-13 | — | — | US | disclosed |
| US-8253130-B2 | Organic electroluminescence device | FUJIFILM CORPORATION (JP) | 2012-08-28 | — | — | US | disclosed |
| US-20110073848-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | FUJIFILM CORPORATION (JP) | 2011-03-31 | — | — | US | disclosed |
| US-20100291689-A1 | Lanthanide Complexes as Fluorescent Indicators for Neutral Sugars and Cancer Diagnosis | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY & AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110073848-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | L1CAM, CYBA, EPCAM | KDM4E 2517/4885GPR3 3296/4885GABRA1 2660/4885 |
| US-20100291689-A1 | Lanthanide Complexes as Fluorescent Indicators for Neutral Sugars and Cancer Diagnosis | LPAR3, LPCAT1, LYPLAL1 | KDM4E 3462/4885GPR3 420/4885GABRA1 4168/4885 |
| US-20120313089-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | L1CAM, CYBA, EPCAM | KDM4E 2517/4885GPR3 3296/4885GABRA1 2660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.