Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086443 | 0.86 | GPR3 (0.41) | ACHEBCHECHRM2HTR1AADRA2A | |
| SCHEMBL7197597 | 0.83 | ACHE (0.49) | ACHEBCHECHRM2HTR1AADRA2A | |
| SCHEMBL7576879 | 0.79 | ACHE (0.45) | ACHEBCHECHRM2HTR1AADRA2A | |
| SCHEMBL2339323 | 0.79 | ACHE (0.45) | ACHEBCHECHRM2HTR1AADRA2A | |
| SCHEMBL27461593 | 0.76 | GPR3 (0.34) | ACHEBCHECHRM2HTR1AADRA2A | |
| SCHEMBL7577807 | 0.75 | ACHE (0.43) | ACHEBCHECHRM2HTR1AADRA2A | |
| SCHEMBL28301540 | 0.73 | ACHE (0.42) | ACHEBCHECHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL10317919 | 0.71 | BCHE (0.35) | ACHEBCHE | |
| SCHEMBL6671925 | 0.71 | GPR3 (0.46) | ACHEBCHECHRM2HTR1AADRA2A | |
| SCHEMBL30390148 | 0.71 | GPR3 (0.46) | ACHEBCHECHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009149906-A2 | PREPARATION OF SILOXY-BRIDGED METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2009-12-17 | — | — | WO | disclosed |
| US-7544825-B1 | Preparation of siloxy-bridged metallocenes | BASELL POLYOLEFINE GMBH (DE) | 2009-06-09 | — | — | US | disclosed |