Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034020 | 0.86 | ACHE (0.47) | GPR3HTR2AACHECHRM2HTR1A | |
| SCHEMBL5981387 | 0.78 | GPR3 (0.46) | GPR3HTR2AACHECHRM2HTR1A | |
| SCHEMBL30390148 | 0.78 | GPR3 (0.46) | GPR3HTR2AACHECHRM2HTR1A | |
| SCHEMBL6671925 | 0.78 | GPR3 (0.46) | GPR3HTR2AACHECHRM2HTR1A | |
| SCHEMBL5175634 | 0.78 | GPR3 (0.46) | GPR3HTR2AACHECHRM2HTR1A | |
| SCHEMBL7575215 | 0.75 | PSEN1 (0.33) | GPR3HTR2AACHECHRM2HTR1A | |
| SCHEMBL7048563 | 0.74 | GPR3 (0.43) | GPR3HTR2AACHECHRM2HTR1A | |
| SCHEMBL6672430 | 0.74 | GPR3 (0.43) | GPR3HTR2AACHECHRM2HTR1A | |
| Hydrochloric Acid SCHEMBL6559588 | 0.74 | GPR3 (0.43) | GPR3HTR2AACHECHRM2HTR1A | |
| Hydrochloric Acid SCHEMBL6559595 | 0.74 | GPR3 (0.43) | GPR3HTR2AACHECHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114556-A | Metallocene compound and its use as catalyst component | TARGOR GMBH (DE) | 2000-09-05 | — | — | US | disclosed |
| US-5962359-A | Metallocene compound and its use as catalyst component | TARGOR GMBH (DE) | 1999-10-05 | — | — | US | disclosed |
| EP-0723971-A2 | Metallocenes and their use as catalyst component | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-31 | — | — | EP | disclosed |